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Evidence-Based Complementary and Alternative Medicine
Volume 2012, Article ID 762918, 9 pages
http://dx.doi.org/10.1155/2012/762918
Research Article

Effectiveness of the Novel Herbal Medicine, KIOM-MA, and Its Bioconversion Product, KIOM-MA128, on the Treatment of Atopic Dermatitis

1Center for Herbal Medicine Improvement Research, Korea Institute of Oriental Medicine (KIOM), 483 Expo-ro, Yuseong-gu, Daejeon 305-811, Republic of Korea
2College of Pharmacy, Sahmyook University, 26-21 Kongnung 2-dong, Nowon-gu, Seoul 139-742, Republic of Korea
3Regional Food Industry Research Group, Korea Food Research Institute, Sungnam 463-746, Republic of Korea

Received 23 August 2011; Accepted 10 October 2011

Academic Editor: Olumayokun A. Olajide

Copyright © 2012 Tae Ho Chung et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [15 citations]

The following is the list of published articles that have cited the current article.

  • Jun-Ho Lee, Jong-Hyun Lee, and Jong-Sik Jin, “Fermentation of traditional medicine: present and future,” Oriental Pharmacy and Experimental Medicine, vol. 12, no. 3, pp. 163–165, 2012. View at Publisher · View at Google Scholar
  • You-Chang Oh, Won-Kyung Cho, Yun Hee Jeong, Ga Young Im, Aeyung Kim, Youn-Hwan Hwang, Taesoo Kim, Kwang Hoon Song, and Jin Yeul Ma, “A Novel Herbal Medicine KIOM-MA Exerts an Anti-Inflammatory Effect in LPS-Stimulated RAW 264.7 Macrophage Cells,” Evidence-Based Complementary and Alternative Medicine, vol. 2012, pp. 1–11, 2012. View at Publisher · View at Google Scholar
  • Mao-Qiang Man, Melanie Hupe, Richard Sun, George Man, Theodora M. Mauro, and Peter M. Elias, “Topical Apigenin Alleviates Cutaneous Inflammation in Murine Models,” Evidence-Based Complementary and Alternative Medicine, vol. 2012, pp. 1–7, 2012. View at Publisher · View at Google Scholar
  • Hyun Ju Cha, Jin Yeul Ma, and Jin-Chul Kim, “In vitro small intestinal absorption and pH stability of tableted KIOM-C and KIOM-MA-128,” Korean Journal of Chemical Engineering, vol. 30, no. 10, pp. 1929–1933, 2013. View at Publisher · View at Google Scholar
  • Aeyung Kim, and Jin Yeul Ma, “Anti-melanogenic activity of the novel herbal medicine, MA128, through inhibition of tyrosinase activity mediated by the p38 mitogen-activated protein kinases and protein kinase signaling pathway in B16F10 cells,” Pharmacognosy Magazine, vol. 10, no. 39, pp. 463–471, 2014. View at Publisher · View at Google Scholar
  • Aeyung Kim, Minju Im, Nam-Hiu Yim, Youn-Hwan Hwang, Hye Jin Yang, and Jin Yeul Ma, “The novel herbal cocktail MA128 suppresses tumor growth and the metastatic potential of highly malignant tumor cells,” Oncology Reports, vol. 34, no. 2, pp. 900–912, 2015. View at Publisher · View at Google Scholar
  • Hyun-moon Back, Byungjeong Song, Jung-woo Chae, Hwi-yeol Yun, Jin Yeul Ma, and Kwang-il Kwon, “Determination of Matrine in Rat Plasma after Oral Administration of Novel Korean Herbal Medicine KIOM-MA128 and Application of PK,” Journal of Analytical Methods in Chemistry, vol. 2015, pp. 1–6, 2015. View at Publisher · View at Google Scholar
  • Kwang Park, Dong Kim, Jae Yoo, and Jin Ma, “The Herbal Medicine KIOM-MA128 Inhibits the Antigen/IgE-Mediated Allergic Response in Vitro and in Vivo,” Molecules, vol. 21, no. 8, pp. 1015, 2016. View at Publisher · View at Google Scholar
  • Jae-Myung Yoo, Ju Hye Yang, Hye Jin Yang, Won-Kyung Cho, and Jin Yeul Ma, “Inhibitory effect of fermented Arctium lappa fruit extract on the IgE-mediated allergic response in RBL-2H3 cells,” International Journal Of Molecular Medicine, vol. 37, no. 2, pp. 501–508, 2016. View at Publisher · View at Google Scholar
  • Dong Gun Kim, Bo Hyoung Lee, Kwang Il Park, and Jin Yeul Ma, “Fermented Herbal Formulas KIOM-MA128 Ameliorate IL-6-Induced Intestinal Barrier Dysfunction in Colon Cancer Cell Line,” Mediators of Inflammation, vol. 2016, 2016. View at Publisher · View at Google Scholar
  • Jae-Myung Yoo, Ju-Hye Yang, Young Soo Kim, Won-Kyung Cho, and Jin Yeul Ma, “ Inhibitory Effect of Loranthus parasiticus on IgE-Mediated Allergic Responses in RBL-2H3 Cells ,” Mediators of Inflammation, vol. 2016, pp. 1–8, 2016. View at Publisher · View at Google Scholar
  • Jae-Myung Yoo, Kwang-Il Park, Jin-Yeul Ma, Dong-Gun Kim, and Mi-Ra Lee, “Fermented herbal formula KIOM-MA-128 protects against acute colitis induced by dextran sodium sulfate in mice,” BMC Complementary and Alternative Medicine, vol. 17, no. 1, 2017. View at Publisher · View at Google Scholar
  • Seung Hyun Kim, Ki Man Lee, Geum Seon Lee, Ju-Won Seong, and Tae Jin Kang, “ Rifampicin Alleviates Atopic Dermatitis-Like Response in vivo and in vitro ,” Biomolecules & Therapeutics, vol. 25, no. 6, pp. 634–640, 2017. View at Publisher · View at Google Scholar
  • Jae-Myung Yoo, Kwang Il Park, Ju-Hye Yang, Won-Kyung Cho, Bohyoung Lee, and Jin Yeul Ma, “Anti-allergic actions of F-PASA, a novel herbal cocktail, in IgE/antigen-mediated allergic responses in RBL-2H3 cells and passive cutaneous anaphylaxis in mice,” Phytomedicine, 2018. View at Publisher · View at Google Scholar
  • Sang-sun Hur, Suk-won Choi, Dong-ryul Lee, Jong-hwan Park, and Tae-ho Chung, “ Advanced Effect of Moringa oleifera Bioconversion by Rhizopus oligosporus on the Treatment of Atopic Dermatitis: Preliminary Study ,” Evidence-Based Complementary and Alternative Medicine, vol. 2018, pp. 1–9, 2018. View at Publisher · View at Google Scholar