7𝜶-Hydroxy-𝜷-Sitosterol from Chisocheton tomentosus Induces Apoptosis via Dysregulation of Cellular Bax/Bcl-2 Ratio and Cell Cycle Arrest by Downregulating ERK1/2 Activation

Figure 5

Wound healing assay displaying the antimigration effects of CT1 on HSC-4 cells, with minimal effects on MCF-7 cells. All cells were treated with mitomycin c to halt proliferation, followed by CT1 at IC₅₀ concentrations for 12 h. Wound edge images of each independent triplicate were captured and measured at 24 h aftertreatment using T-scratch software, and percentage of migration is indicated as mean ± SEM.