Evidence-Based Complementary and Alternative Medicine

Research Article

Activation of Spinal 𝜶 2-Adrenoceptors Using Diluted Bee Venom Stimulation Reduces Cold Allodynia in Neuropathic Pain Rats

Table 1

Effect of single DBV injection on accelerating rota-rod performance.
GroupPrePost60 m120 m240 m
CCI (Saline) 1 0 0 . 2 4 ± 4 . 6 7 5 3 . 9 4 ± 5 . 3 3 5 2 . 5 1 ± 7 . 1 3 5 8 . 1 8 ± 8 . 6 8 5 6 . 2 5 ± 8 . 3 2
CCI (DBV: 2.5 mg) 1 0 3 . 1 4 ± 8 . 7 6 5 6 . 3 1 ± 5 . 3 6 3 1 . 9 1 ± 1 . 9 9 ** 3 6 . 4 9 ± 3 . 0 5 * 5 1 . 3 0 ± 2 . 0 2
CCI (DBV: 0.25 mg) 1 1 6 . 6 8 ± 6 . 0 7 5 3 . 7 0 ± 4 . 2 3 5 1 . 2 9 ± 3 . 9 4 4 9 . 9 3 ± 5 . 1 7 6 0 . 2 8 ± 8 . 1 8
CCI (Saline): saline-treated CCI surgery animal group ( 𝑛 = 6 ), CCI (DBV: 2.5 mg): DBV 2.5 mg/kg treated CCI surgery animal group ( 𝑛 = 6 ), CCI (DBV: 0.25 mg): DBV 0.25 mg/kg treated CCI surgery animal group ( 𝑛 = 6 ) Pre: presurgery, Post: 2 weeks after CCI surgery, 60 m–240 m: minutes 60–240 after saline or DBV treatment.