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| Included studies | Methods | Participants | Interventions | Outcomes |
| Date of study | First author | Double-blind | Settings | | Age (years) | Gender | Experiment group | Control group | Death | Clinical status | Quality of life | Hemorheology | Adverse effect |
|
| 1999 | Chen | Yes | H | 72/52 | 45–85 | M, F | Conventional medicine treatment plus ligustrazine injection 200–240 mg qd. 14 days | Conventional medicine treatment | NK | Yes | No | No | NK |
|
| 2010 | Chen | No | H | 46/46 | 61–77 | M, F | Conventional medicine treatment plus ligustrazine injection 100 mg qd. 14 days | Conventional medicine treatment | NK | Yes | No | No | NK |
|
| 2010 | Yuan | No | H | 31/31 | NK | M, F | Conventional medicine treatment plus Ligustrazine Hydrochloride injection 40 mL, 60 mL qd. 14 days | Conventional medicine treatment | No | Yes | No | Yes | NK |
|
| 2009 | Bai | No | H | 35/35 | 58–80 | M, F | Conventional medicine treatment plus ligustrazine injection 80 mg qd. 14 days | Conventional medicine treatment | No | Yes | No | Yes | No |
|
| 2009 | An | No | H | 40/38 | 59–81 | M, F | Conventional medicine treatment plus ligustrazine injection 120 mg qd. 14 days | Conventional medicine treatment | NK | Yes | No | No | NK |
|
| 2009 | Hao | No | H | 50/50 | 55–75 | M, F | Conventional medicine treatment plus ligustrazine injection 400 mg qd. 10 days | Conventional medicine treatment | NK | Yes | No | No | NK |
|
| 2009 | Wu | No | H | 30/30 | | M, F | Conventional medicine treatment plus ligustrazine injection 400 mg qd. 10 days | Conventional medicine treatment | NK | Yes | No | No | NK |
|
| 2009 | Wu | No | H | 40/40 | 50–70 | M, F | Conventional medicine treatment plus ligustrazine injection 800 mg qd. 7 days | Conventional medicine treatment | NK | No | No | No | NK |
|
| 2009 | Ma | No | H | 36/36 | 48–82 | M, F | Conventional medicine treatment plus ligustrazine injection 400 mg qd. 14 days | Conventional medicine treatment | NK | Yes | No | No | NK |
|
| 2008 | Li | No | H | 31/30 | | M, F | Conventional medicine treatment plus ligustrazine injection 100 mg qd. 10 days | Conventional medicine treatment | NK | Yes | No | No | NK |
|
| 2008 | Liu | No | H | 38/36 | Mean 65.2/65.6 | M, F | Conventional medicine treatment plus ligustrazine injection 120–240 mg qd. 10 days | Conventional medicine treatment | NK | Yes | No | Yes | NK |
|
| 2008 | Qi | No | H | 34/30 | 57–82 | M, F | Conventional medicine treatment plus ligustrazine injection 100 mL. qd 14 days | Conventional medicine treatment | No | Yes | No | Yes | NK |
|
| 2008 | Ye | No | H | 32/32 | | M, F | Conventional medicine treatment plus ligustrazine injection 120 mg. qd 10 days | Conventional medicine treatment | No | Yes | No | No | No |
|
| 2008 | Xie | No | H | 56/49 | 36–75 Mean 66.5/38–77 Mean 67 | M, F | Conventional medicine treatment plus ligustrazine injection 80 mg. qd or bid. 10–14 days | Conventional medicine treatment | NK | Yes | No | Yes | NK |
|
| 2007 | Fan | No | H | 22/21 | | M, F | Conventional medicine treatment plus Ligustrazine Hydrochloride injection 100 mL. qd. 14 days | Conventional medicine treatment | No | Yes | No | Yes | Yes |
|
| 2007 | Sun | No | H | 40/40 | 63.67 ± 14.15/67.25 ± 10.64 | M, F | Conventional medicine treatment plus Ligustrazine Hydrochloride injection 160 mg. qd. 14 days | Conventional medicine treatment | NK | Yes | No | Yes | NK |
|
| 2006 | Shui | No | H | 31/28 | | M, F | Conventional medicine treatment plus ligustrazine injection 400 mg. qd. 7 days | Conventional medicine treatment | NK | Yes | No | Yes | NK |
|
| 2006 | Wei | No | H | 29/22 | 59–81 | M, F | Conventional medicine treatment plus ligustrazine injection 80 mg. qd. 7 days | Conventional medicine treatment | NK | Yes | No | No | NK |
|
| 2006 | Zhu | No | Out patient | 12/12 | 47–85 | M, F | Conventional medicine treatment plus ligustrazine injection 80 mg. qd. 10 days | Conventional medicine treatment | NK | Yes | No | No | No |
|
| 2006 | Wang | No | H | 120/80 | 40–85 | M, F | Conventional medicine treatment plus ligustrazine injection 100 mg. qd. 10–15 days | Conventional medicine treatment | NK | Yes | No | Yes | NK |
|
| 2006 | Xu | No | H | 36/34 | 56–82, | M, F | Conventional medicine treatment plus ligustrazine injection 160 mg. qd. 10 days | Conventional medicine treatment | NK | Yes | No | No | NK |
|
| 2005 | Huang | No | H | 30/30 | 49–71 | M, F | Conventional medicine treatment plus ligustrazine injection 80 mg. qd. 10 days | Conventional medicine treatment | Nk | Yes | No | No | Nk |
|
| 2005 | Liu | No | H | 30/30 | 59–75, | M, F | Conventional medicine treatment plus ligustrazine injection 400 mg. qd. 10–14 days | Conventional medicine treatment | NK | Yes | No | Yes | No |
|
| 2005 | Pan | No | H | 16/16 | 60–89 | M, F | Conventional medicine treatment plus ligustrazine injection 160 mg. qd. 14 days | Conventional medicine treatment | NK | Yes | No | Yes | NK |
|
| 2004 | Gao | No | H | 23/20 | 55–80 | M, F | Conventional medicine treatment plus ligustrazine injection 80 mg. qd. 15 days | Conventional medicine treatment | Yes | Yes | No | No | No |
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| 2004 | Ma | No | H | 30/30 | 50–70 | M, F | Conventional medicine treatment plus ligustrazine injection 800 mg. qd. 7 days | Conventional medicine treatment | No | Yes | No | No | NK |
|
| 2004 | Zhang | No | H | 30/25 | 53–79 | M, F | Conventional medicine treatment plus ligustrazine injection 200 mg. qd. 10 days | Conventional medicine treatment | No | Yes | No | No | NK |
|
| 2003 | Liu | No | H | 26/26 | 56–82 | M, F | Conventional medicine treatment plus ligustrazine injection 200 mg. qd. 14 days | Conventional medicine treatment | No | Yes | No | Yes | NO |
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| 2001 | Xia | No | H | 47/41 | 58–73 | M, F | Conventional medicine treatment plus ligustrazine injection 200–240 mg. qd. 14 days | Conventional medicine treatment | NK | Yes | No | No | No |
|
| 2001 | Zhu | No | H | 30/30 | stratified | M, F | Conventional medicine treatment plus ligustrazine injection 800 mg. qd. 10 days | Conventional medicine treatment | Yes | Yes | No | Yes | No |
|
| 2000 | Sun | No | H | 36/36 | NK | M, F | Conventional medicine treatment plus ligustrazine injection 400 mg. qd. 14 days | Conventional medicine treatment | No | Yes | No | No | NK |
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| 1994 | Wang | No | H | 26/26 | 37–77 | M, F | Conventional medicine treatment plus ligustrazine injection 160 mg. qd. 10 days | Conventional medicine treatment | NK | No | No | No | No |
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| 2008 | Zhou | No | H | 49/47 | NK | M, F | Conventional medicine treatment plus ligustrazine injection 80 mg. qd. 10 days | Conventional medicine treatment | NK | Yes | No | No | No |
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