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Evidence-Based Complementary and Alternative Medicine
Volume 2012 (2012), Article ID 794970, 13 pages
Research Article

In Vivo Anti-Influenza Virus Activity of Japanese Herbal (Kampo) Medicine, “Shahakusan,” and Its Possible Mode of Action

1Graduate School of Infection Control Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan
2Department of Drug Discovery Sciences, Kitasato Institute for Life Sciences, Kitasato University, 5-9-1 Shirakane, Minato-ku, Tokyo 108-8641, Japan
3Department of Basic Research, Oriental Medicine Research Center, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8642, Japan

Received 26 June 2012; Revised 20 November 2012; Accepted 30 November 2012

Academic Editor: Taixiang Wu

Copyright © 2012 Rei Hokari et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [5 citations]

The following is the list of published articles that have cited the current article.

  • Dhivya Rajasekaran, Enzo A. Palombo, Tiong Chia Yeo, Diana Lim Siok Ley, Chu Lee Tu, Francois Malherbe, and Lara Grollo, “Identification of Traditional Medicinal Plant Extracts with Novel Anti-Influenza Activity,” Plos One, vol. 8, no. 11, 2013. View at Publisher · View at Google Scholar
  • Takayuki Nagai, Erika Kataoka, Yuka Aoki, Rei Hokari, Hiroaki Kiyohara, and Haruki Yamada, “Alleviative Effects of a Kampo (a Japanese Herbal) Medicine “Maoto (Ma-Huang-Tang)” on the Early Phase of Influenza Virus Infection and Its Possible Mode of Action,” Evidence-Based Complementary and Alternative Medicine, vol. 2014, pp. 1–12, 2014. View at Publisher · View at Google Scholar
  • Gansukh Enkhtaivan, K.M. Maria John, Muniappan Ayyanar, Thangavel Sekar, Ki-Joun Jin, and Doo Hwan Kim, “Anti-influenza (H1N1) potential of leaf and stem bark extracts of selected medicinal plants of South India,” Saudi Journal of Biological Sciences, 2015. View at Publisher · View at Google Scholar
  • Xin-yan Qu, Qing-jun Li, Hui-min Zhang, Xiao-juan Zhang, Peng-hui Shi, Xiu-juan Zhang, Jing Yang, Zhe Zhou, and Sheng-qi Wang, “Protective effects of phillyrin against influenza A virus in vivo,” Archives of Pharmacal Research, 2016. View at Publisher · View at Google Scholar
  • Yuri Harada, Takeshi Tsuruta, Yuriko Oda, Fumitaka Ueda, Takamitsu Tsukahara, Yasuhiro Tsukamoto, Ryo Inoue, Gustavo A. Romero-Pérez, and Masayo Egashira, “Orally Administered Salacia reticulata Extract Reduces H1N1 Influenza Clinical Symptoms in Murine Lung Tissues Putatively Due to Enhanced Natural Killer Cell Activity,” Frontiers in Immunology, vol. 7, 2016. View at Publisher · View at Google Scholar