In Vivo Anti-Influenza Virus Activity of Japanese Herbal (Kampo) Medicine, “Shahakusan,” and Its Possible Mode of Action
Effect of SHS treatment on the lung tissue of influenza virus infected mice (lower respiratory tract infection). Representative histologic sections of lungs harvested at 4 day p.i. and stained with hematoxylin and eosin. Mock-infected BALB/c mice were administered orally with water as a control (a), and influenza virus infected mice were administered orally with water (b) or SHS (c) from one day before to 3 days p.i. as shown in Figure 2(b). Thin arrow indicates infiltration of inflammatory cells. Open arrow indicates desquamated mucosal epithelia. Magnification 200x.