The Components of Flemingia macrophylla Attenuate Amyloid β-Protein Accumulation by Regulating Amyloid β-Protein Metabolic Pathway
Figure 6
Aβ1-40 accumulation reduced by the fractions and flavonoids was differentially recovered by bacitracin. (a) swAPP770-transfected N2a cells were treated with the fractions and flavonoids for 20 h at NTC, in the absence (closed columns) and presence (opened columns) of 2 nM bacitracin. The level of extracellular Aβ1-40 was determined by ELISA. (b) The recovery effect of bacitracin was calculated by the subtraction between the levels of the cells treated with and without bacitracin. Results are means ± SD from three independent experiments. Significant differences between control and FM fractions-treated cells are indicated by ***.
