Anti-Inflammatory and Anticoagulative Effects of Paeonol on LPS-Induced Acute Lung Injury in Rats

Table 1

Effect of paeonol on the histopathological scores in lipopolysaccharide-induced acute lung injury.

	Cellularity	Protein exudation	Hemorrhage	Scores
PBS-DMSO	7.2±1.0	3.8±0.6	8.1±1.8	19.0±2.5
PBS-paeonol	4.5±0.2	2.7±0.6	7.8±0.7	14.9±1.2
LPS-DMSO	18.0±0.7	10.9±0.8	16.4±1.0	45.4±1.0
LPS-paeonol-25	10.8±0.9^#	4.5±0.8^#	11.5±1.5	26.8±2.4^#
LPS-paeonol-50	9.1±1.2^#	4.1±0.4^#	10.5±1.5^#	23.7±2.9^#

Data are presented as mean ± SEM; PBS-DMSO: PBS-DMSO group; PBS-paeonol: PBS-paeonol group; LPS-DMSO: LPS-DMSO group; LPS-paeonol-25: LPS-paeonol-25 mg/kg group; LPS-paeonol-50: LPS-paeonol-50 mg/kg group; ^#𝑃<0.05 compared with LPS-DMSO; 𝑛=6.