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Evidence-Based Complementary and Alternative Medicine
Volume 2012, Article ID 837958, 7 pages
Research Article

Comparison of the Effects on Rib Fracture between the Traditional Japanese Medicine Jidabokuippo and Nonsteroidal Anti-Inflammatory Drugs: A Randomized Controlled Trial

1Department of Emergency and Critical Care Medicine, Akita University Graduate School of Medicine, 1-1-1 Hondo, Akita 010-8543, Japan
2Department of Traditional Japanese Medicine, Akita University Hospital, 1-1-1 Hondo, Akita 010-8543, Japan
3Division of Orthopedics, Minamiakita Orthopedic Clinic, 96-2 Kaidoshita, Syowaokubo, Katagami 018-1401, Japan
4Division of Orthopedics, Yuzawa Clinic, 3-22 Satake Cho, Yuzawa 012-0824, Japan

Received 25 April 2012; Accepted 11 June 2012

Academic Editor: Raffaele Capasso

Copyright © 2012 Hajime Nakae et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Jidabokuippo is a traditional Japanese medicine used for contusion-induced swelling and pain. This open multicenter randomized study was designed to compare the efficacies of jidabokuippo and nonsteroidal anti-inflammatory drugs (NSAIDs) in patients with rib fracture by analyzing the treatment duration. Our study involved 170 rib fracture patients capable of oral ingestion divided randomly into 2 groups: the jidabokuippo and NSAID groups. We compared the duration of treatment and healthcare expenditure between these 2 groups. Medication was continued in both groups until the visual analogue scale score decreased to less than 50% of the pretreatment score. We excluded the patients in whom medication was prematurely discontinued. We analyzed 81 patients belonging to the jidabokuippo and NSAIDs groups. No significant intergroup differences were observed in age, gender, severity (injury severity score), and presence/absence of underlying disease. The treatment duration was significantly shorter in the jidabokuippo group than in the NSAIDs group ( ). Healthcare expenditure was significantly lower in the jidabokuippo group than in the NSAIDs group ( ). Our results suggest that compared to NSAIDs, jidabokuippo can shorten the duration of treatment in patients with rib fracture and is a promising analgesic agent based on the medical economic viewpoint.