Table of Contents Author Guidelines Submit a Manuscript
Evidence-Based Complementary and Alternative Medicine
Volume 2012, Article ID 843025, 7 pages
http://dx.doi.org/10.1155/2012/843025
Research Article

Gelam (Melaleuca spp.) Honey-Based Hydrogel as Burn Wound Dressing

1Department of Life Sciences, Faculty of Pharmacy, Universiti Teknologi MARA, 42300 Puncak Alam, Selangor, Malaysia
2Department of Veterinary Preclinical Sciences, Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia
3Division of Agrotechnology and Biosciences, Malaysian Nuclear Agency, Bangi, 43000 Kajang, Selangor, Malaysia
4Department of Veterinary Microbiology and Pathology, Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia
5Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia

Received 28 April 2011; Accepted 4 July 2011

Academic Editor: Ronald Sherman

Copyright © 2012 Rozaini Mohd Zohdi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. M. Subrahmanyam, “Topical application of honey for burn wound treatment-an overview,” Annals of Burns and Fire Disasters, vol. 20, no. 3, pp. 322–333, 2007. View at Google Scholar
  2. P. C. Molan, “The role of honey in the management of wounds,” Journal of wound care, vol. 8, no. 8, pp. 415–418, 1999. View at Google Scholar · View at Scopus
  3. O. Sherlock, A. Dolan, R. Athman et al., “Comparison of the antimicrobial activity of Ulmo honey from Chile and Manuka honey against methicillin-resistant Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa,” BMC Complementary and Alternative Medicine, vol. 10, no. 47, pp. 1–5, 2010. View at Publisher · View at Google Scholar · View at Scopus
  4. R. A. Cooper, P. C. Molan, and K. G. Harding, “Antibacterial activity of honey against strains of Staphylococcus aureus from infected wounds,” Journal of the Royal Society of Medicine, vol. 92, no. 6, pp. 283–285, 1999. View at Google Scholar · View at Scopus
  5. B. G. Visavadia, J. Honeysett, and M. H. Danford, “Manuka honey dressing: an effective treatment for chronic wound infections,” British Journal of Oral and Maxillofacial Surgery, vol. 46, no. 1, pp. 55–56, 2008. View at Publisher · View at Google Scholar · View at Scopus
  6. P. C. Molan, “Using honey in wound care,” International Journal of Clinical Aromatheraphy France, vol. 3, no. 3, pp. 21–24, 2006. View at Google Scholar
  7. A. Henriques, S. Jackson, R. Cooper, and N. Burton, “Free radical production and quenching in honeys with wound healing potential,” Journal of Antimicrobial Chemotherapy, vol. 58, no. 4, pp. 773–777, 2006. View at Publisher · View at Google Scholar · View at Scopus
  8. N. Yusof, J. Haryati, A. M. Salahbiah et al., “Selection of local honey for wound dressing,” in Proceedings of MINT R&D Seminar, pp. 17–19, 2000.
  9. N. M. Nasir, A. S. Halim, K. K. B. Singh, A. A. Dorai, and M. N. M. Haneef, “Antibacterial properties of tualang honey and its effect in burn wound management: a comparative study,” BMC Complementary and Alternative Medicine, vol. 10, no. 31, pp. 1–7, 2010. View at Publisher · View at Google Scholar · View at Scopus
  10. A. M. Aljady, M. Y. Kamaruddin, A. M. Jamal, and M. Y. Mohd-Yassim, “Biochemical study on the efficacy of Malaysian Honey on inflicted wounds: an animal model,” Medical Journal of Islamic Academy of Sciences, vol. 13, no. 3, pp. 125–132, 2000. View at Google Scholar
  11. Y. T. Khoo, A. S. Halim, K. B. Singh, and N. A. Mohamad, “Wound contraction effects and antibacterial properties of Tualang honey on full-thickness burn wounds in rats in comparison to hydrofibre,” BMC Complementary and Alternative Medicine, vol. 10, no. 48, pp. 1–8, 2010. View at Publisher · View at Google Scholar · View at Scopus
  12. A. M. Aljadi and M. Y. Kamaruddin, “Evaluation of the phenolic contents and antioxidant capacities of two Malaysian floral honeys,” Food Chemistry, vol. 85, no. 4, pp. 513–518, 2004. View at Publisher · View at Google Scholar · View at Scopus
  13. M. Kassim, M. Achoui, M. Mansor, and K. M. Yusoff, “The inhibitory effects of Gelam honey and its extracts on nitric oxide and prostaglandin E2 in inflammatory tissues,” Fitoterapia, vol. 81, no. 8, pp. 1196–1201, 2010. View at Publisher · View at Google Scholar · View at Scopus
  14. M. Z. Rozaini, A. B. Z. Zuki, M. M. Noordin, Y. Norimah, and M. N. H. Abdullah, “The effect of topical application of Malaysian honey on burn wound healing,” Jurnal Veterinar Malaysia, vol. 2004, no. 1-2, pp. 47–50, 2004. View at Google Scholar
  15. A. S. Hoffman, “Hydrogels for biomedical applications,” Advanced Drug Delivery Reviews, vol. 54, no. 1, pp. 3–12, 2002. View at Publisher · View at Google Scholar · View at Scopus
  16. V. Rattanaruengsrikul, N. Pimpha, and P. Supaphol, “Development of gelatin hydrogel pads as antibacterial wound dressings,” Macromolecular Bioscience, vol. 9, no. 10, pp. 1004–1015, 2009. View at Publisher · View at Google Scholar · View at Scopus
  17. B. Singh and L. Pal, “Radiation crosslinking polymerization of sterculia polysaccharide-PVA-PVP for making hydrogel wound dressings,” International Journal of Biological Macromolecules, vol. 48, no. 3, pp. 501–510, 2011. View at Publisher · View at Google Scholar
  18. R. M. Zohdi, Z. A. B Zakaria, N. Yusof, N. M. Mustapha, and M. N. H. Abdullah, “Sea cucumber (Stichopus hermanii) based hydrogel to treat burn wounds in rats,” Journal of Biomedical Materials Research Part B, vol. 98, no. 1, pp. 30–37, 2011. View at Publisher · View at Google Scholar
  19. J. M. Yang, W. Y. Su, T. L. Leu, and M. C. Yang, “Evaluation of chitosan/PVA blended hydrogel membranes,” Journal of Membrane Science, vol. 236, no. 1-2, pp. 39–51, 2004. View at Publisher · View at Google Scholar · View at Scopus
  20. W. J. Cho, O. S. Heang, and L. J. Ho, “Alginate film as a novel post-surgical tissue adhesion barrier,” Journal of Biomaterials Science, vol. 21, no. 6-7, pp. 701–713, 2010. View at Publisher · View at Google Scholar · View at Scopus
  21. R. Jayakumar, M. Prabaharan, S. V. Nair, and H. Tamura, “Novel chitin and chitosan nanofibers in biomedical applications,” Biotechnology Advances, vol. 28, no. 1, pp. 142–150, 2010. View at Publisher · View at Google Scholar · View at Scopus
  22. N. Yusof, A. H. Ainul Hafiza, R. M. Zohdi, and M. Z. A. Bakar, “Development of honey hydrogel dressing for enhanced wound healing,” Radiation Physics and Chemistry, vol. 76, no. 11-12, pp. 1767–1770, 2007. View at Publisher · View at Google Scholar · View at Scopus
  23. M. Z. Rozaini, A. B. Z. Zuki, M. M. Noordin, N. Yusof, and M. N. H. Abdullah, “The effects of different types of honey on tensile strength evaluation of burn wound tissue healing,” International Journal of Applied Research Veterinary Medicine, vol. 2, no. 4, pp. 290–296, 2004. View at Google Scholar
  24. D. Bryan, K. B. Walker, M. Ferguson, and R. Thorpe, “Cytokine gene expression in a murine wound healing model,” Cytokine, vol. 31, no. 6, pp. 429–438, 2005. View at Publisher · View at Google Scholar · View at Scopus
  25. D. Parsons, P. G. Bowler, V. Myles, and S. Jones, “Silver antimicrobial dressings in wound management: a comparison of antibacterial, physical, and chemical characteristics,” Wounds, vol. 17, no. 8, pp. 222–232, 2005. View at Google Scholar · View at Scopus
  26. P. C. Molan, “Establishing honey as a recognized medicine,” The Journal of the American Apitherapy Society, vol. 7, no. 1, pp. 7–9, 2000. View at Google Scholar
  27. N. Mao and S. J. Russell, “Nonwoven wound dressings,” Textile Progress, vol. 36, no. 4, pp. 41–57, 2004. View at Publisher · View at Google Scholar · View at Scopus
  28. M. Kokabi, M. Sirousazar, and Z. M. Hassan, “PVA-clay nanocomposite hydrogels for wound dressing,” European Polymer Journal, vol. 43, no. 3, pp. 773–781, 2007. View at Publisher · View at Google Scholar · View at Scopus
  29. P. C. Molan, “Re-introducing honey in the management of wounds and ulcers—theory and practice,” Ostomy/Wound Management, vol. 48, no. 11, pp. 28–40, 2002. View at Google Scholar · View at Scopus
  30. N. Pejnovic, D. Lilic, G. Zunic, M. Colic, M. Kataranovski, and A. Dujic, “Aberrant levels of cytokines within the healing wound after burn injury,” Archives of Surgery, vol. 130, no. 9, pp. 999–1006, 1995. View at Google Scholar · View at Scopus
  31. J. Tian, K. K. Y. Wong, C. M. Ho et al., “Topical delivery of silver nanoparticles promotes wound healing,” ChemMedChem, vol. 2, no. 1, pp. 129–136, 2007. View at Publisher · View at Google Scholar · View at Scopus