Review Article
Green Tea Polyphenols for the Protection against Renal Damage Caused by Oxidative Stress
Table 7
Renal functional parameters at 50 days of administration.
| Items | Normal | Control | (−)-Epigallocatechin 3-O-gallate | 25 mg/kg B.W./day | 50 mg/kg B.W./day | 100 mg/kg B.W./day |
| Serum urea nitrogen (mg/dL) | 16.8 ± 0.5 | 44.5 ± 3.1b | 37.9 ± 1.8b,d | 38.0 ± 2.6b,d | 28.8 ± 1.4b,d | Serum Cr (mg/dL) | 0.38 ± 0.01 | 0.94 ± 0.09b | 0.90 ± 0.08b | 0.82 ± 0.06b | 0.66 ± 0.05b,d | Ccr (ml/kg B.W./min) | 7.20 ± 0.26 | 3.35 ± 0.43b | 3.41 ± 0.32b | 3.65 ± 0.37b | 4.09 ± 0.35b,c | Urinary protein (mg/day) | 19.1 ± 0.7 | 82.3 ± 13.3b | 64.0 ± 11.9b | 47.9 ± 14.6a,d | 40.6 ± 6.4d |
|
|
Significance: a, b versus normal values; c, d versus diabetic nephropathy control values.
|