Evidence-Based Complementary and Alternative Medicine

Research Article

Pleurotus tuber-regium Polysaccharides Attenuate Hyperglycemia and Oxidative Stress in Experimental Diabetic Rats

Table 3

Changes in bodyweight and weight gain (g) over a period of 8 weeks in three different polysaccharides (1P, 2P, and 3P) supplemented and diabetic plus high-fat diet-fed rats (DHF).
 DHFDHF+1PDHF+2PDHF+3P
Week 0 3 0 2 . 1 2 ± 2 . 1 2 9 0 . 8 2 ± 3 . 4 1 2 9 5 . 6 3 ± 3 . 1 2 9 2 . 3 5 ± 2 . 9
Week 2 3 6 0 . 2 9 ± 3 . 1 3 3 9 . 1 9 ± 2 . 7 6 * 3 4 2 . 5 6 ± 3 . 1 * 3 4 3 . 3 7 ± 2 . 9 7 *
Week 4 4 3 0 . 7 1 ± 3 . 4 4 0 5 . 8 4 ± 3 . 6 7 * 4 0 8 . 4 3 ± 2 . 6 6 * 4 1 0 . 3 8 ± 3 . 2 *
Week 6 4 6 9 . 2 8 ± 3 . 2 4 2 5 . 1 2 ± 3 . 5 4 * 4 2 8 . 4 7 ± 3 . 1 5 * 4 4 2 . 2 4 ± 2 . 9 9 *
Week 8 4 9 9 . 8 ± 2 . 9 4 5 1 . 1 3 ± 3 * 4 5 6 . 5 3 ± 3 . 3 3 * 4 6 0 . 8 7 ± 3 . 1 2 *
Weight gain 1 9 7 . 7 ± 4 1 6 0 . 3 1 ± 4 . 1 * 1 9 0 . 0 9 ± 3 . 5 4 † 1 8 8 . 5 2 ± 3 †#
Values are expressed as mean ± SEM ( 𝑛 = 1 0 ). The ∗ indicates a significant difference compared to DHF group at respective week ( 𝑃 < 0 . 0 1 ), † indicates a significant compared DHF+1P ( 𝑃 < 0 . 0 1 ), and # indicates a significant difference compared to DHF+2P ( 𝑃 < 0 . 0 5 ).