Research Article

Pleurotus tuber-regium Polysaccharides Attenuate Hyperglycemia and Oxidative Stress in Experimental Diabetic Rats

Table 5

Effect of three different polysaccharides (1P, 2P, and 3P) on total cholesterol (TC), triglyceride (TG), HDL, and LDL levels in diabetic rats fed a high-fat diet (DHF).

DHFDHF+1PDHF+2PDHF+3P

TC (mg/dL) 1 5 5 . 7 ± 2 . 5 1 1 9 . 5 ± 2 . 6 * 1 3 1 . 1 ± 3 . 1 *† 1 3 7 . 6 ± 2 . 1 *†#
TG (mg/dL) 1 9 2 . 3 ± 2 . 4 1 7 8 . 9 ± 2 . 8 * 1 8 1 . 7 ± 2 . 5 * 1 8 3 ± 2 . 4 *
HDL (mg/dL) 2 6 . 1 ± 2 . 5 3 3 ± 1 . 8 * 3 0 . 7 ± 2 . 3 * 2 9 . 3 ± 1 . 3 *
LDL (mg/dL) 1 9 1 . 1 ± 3 . 0 1 5 1 ± 1 . 6 * 1 6 4 ± 1 . 5 *† 1 7 1 . 7 ± 2 . 4 *†#

Values are expressed as mean ± SEM ( 𝑛 = 1 0 ). The indicates a significant difference compared to DHF group ( 𝑃 < 0 . 0 5 ), indicates a significant difference compared to DHF+1P ( 𝑃 < 0 . 0 1 ), and # indicates a significant difference compared to DHF+2P ( 𝑃 < 0 . 0 1 ).