Evidence-Based Complementary and Alternative Medicine / 2012 / Article / Tab 1

Research Article

Aqueous Extract of Solanum nigrum Leaf Activates Autophagic Cell Death and Enhances Docetaxel-Induced Cytotoxicity in Human Endometrial Carcinoma Cells

Table 1

Synergistic effect of AE-SN and docetaxel on human endometrial carcinoma cells HEC1A and HEC1B. By analyzing the cytotoxicity on AE-SN and docetaxel co-treated HEC1A and HEC1B cells, the combination index (CI) values were obtained. When the CI value is less than 1, the effect is considered synergistic.

 
 
Docetaxel (nM)
AE-SN (mg/mL)
CI for HEC-1ACI for HEC-1B
0.20.50.20.5

0.00116.755.3633.08162.49
0.0135.2542.3615.78162.49
0.110.4142.3715.84.99
0.53.4324.731.724.99
10.671.080.430.19
50.080.080.060.11
100.060.010.010.03
500.110.020.020.01
1000.190.070.040.02

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