Anticonvulsant Activity of Extracts of Plectranthus barbatus Leaves in Mice

Table 2

Anticonvulsant effects of Plecthranthus barbatus extract on pilocarpine-induced seizures in mice.

Dose (mg/kg) p.o.	Time to seizure onset (s)	Death latency (s)	Death rate (%)
0 (control)	117.1 ± 14.8	194.7 ± 19.9	100
1	300.9 ± 53.3*	364.5 ± 59.4*	100
10	373.9 ± 18.7*	468.1 ± 39.6*	100
30	276.4 ± 20.6*	317.1 ± 26.9	100
100	261.0 ± 29.1*	334.0 ± 25.2*	100

* 𝑃<.05, significant difference compared to control (ANOVA followed by Dunnett’s multiple comparisons test).