Uncaria tomentosa for Reducing Side Effects Caused by Chemotherapy in CRC Patients: Clinical Trial
Table 3
White blood cells count and platelets’s evaluation of the CRC patients in adjuvant/palliative chemotherapy, without Uncaria tomentosa supply (C group) or receiving 300 mg/day of Uncaria tomentosa (UT group).
Parameters
Groups
Chemotherapy cycles
0
1
2
3
4
5
6
WBC
UT
8.178
5.689*
5.184**
4.778**
4.956**
4.660**
4.442**
cells ×109/L
(2.705)
(1.919)
(2.051)
(2.022)
(2.006)
(2.095)
(2.433)
C
7.668
5.933*
5.391*
4.886*
4.473***
4.962**
4.195***
(2.892)
(2.137)
(2.451)
(2.039)
(2.086)
(2.157)
(1.558)
Neutrophils
UT
5.345
3.069*
2.600**
2.441**
2.429**
2.227**
2.343***
cells ×109/L
(2.691)
(1.455)
(1.411)
(1.401)
(1.456)
(1.506)
(1.842)
C
4.871
3.285*
2.848**
2.295***
2.190***
2.514*
1.975***
(2.674)
(1.618)
(1.858)
(2.295)
(1.628)
(1.797)
(1.186)
Lymphocytes
UT
2.038
1.888
1.859
1.673
1.776
1.728
1.433*
cells ×109/L
(.735)
(.681)
(.656)
(.642)
(.661)
(.754)
(.504)
C
1.901
1.888
1.815
1.769
1.650
1.697
1.578
(.702)
(.737)
(.717)
(.827)
(.648)
(.531)
(.659)
Monocytes
UT
.538
.515
.528
.482
.546
.547
.542
cells ×109/L
(.215)
(.157)
(.197)
(.216)
(.244)
(.241)
(.306)
C
.542
.533
.570
.602
.470
.595
.498
(.245)
(.254)
(.254)
(.272)
(.197)
(.262)
(.231)
Platelets
UT
263
188*
174*
146***
135***
117***
117***
count ×109/L
(92)
(43)
(55)
(48)
(51)
(42 )
(33)
C
286
216*
197**
161***
149***
165***
141***
(76)
(68)
(64)
(70 )
(66)
(57)
(58)
Values expressed as mean (SD). UT group: patients treated with FOLFOX4 + Uncaria tomentosa 300 mg/daily (); C group: CRC patients received FOLFOX4 (); *; **; *** in relation to the day 0.