Research Article

Uncaria tomentosa for Reducing Side Effects Caused by Chemotherapy in CRC Patients: Clinical Trial

Table 3

White blood cells count and platelets’s evaluation of the CRC patients in adjuvant/palliative chemotherapy, without Uncaria tomentosa supply (C group) or receiving 300 mg/day of Uncaria tomentosa (UT group).

ParametersGroupsChemotherapy cycles
0123456

WBCUT8.1785.689*5.184**4.778**4.956**4.660**4.442**
cells ×109/L(2.705)(1.919)(2.051)(2.022)(2.006)(2.095)(2.433)
C7.6685.933*5.391*4.886*4.473***4.962**4.195***
(2.892)(2.137)(2.451)(2.039)(2.086)(2.157)(1.558)
NeutrophilsUT5.3453.069*2.600**2.441**2.429**2.227**2.343***
cells ×109/L(2.691)(1.455)(1.411)(1.401)(1.456)(1.506)(1.842)
C4.8713.285*2.848**2.295***2.190***2.514*1.975***
(2.674)(1.618)(1.858)(2.295)(1.628)(1.797)(1.186)
LymphocytesUT2.0381.8881.8591.6731.7761.7281.433*
cells ×109/L(.735)(.681)(.656)(.642)(.661)(.754)(.504)
C1.9011.8881.8151.7691.6501.6971.578
(.702)(.737)(.717)(.827)(.648)(.531)(.659)
MonocytesUT.538.515.528.482.546.547.542
cells ×109/L(.215)(.157)(.197)(.216)(.244)(.241)(.306)
C.542.533.570.602.470.595.498
(.245)(.254)(.254)(.272)(.197)(.262)(.231)
PlateletsUT263188*174*146***135***117***117***
count ×109/L(92)(43)(55)(48)(51)(42 )(33)
C286216*197**161***149***165***141***
(76)(68)(64)(70 )(66)(57)(58)

Values expressed as mean (SD). UT group: patients treated with FOLFOX4 + Uncaria tomentosa 300 mg/daily ( ); C group: CRC patients received FOLFOX4 ( ); * ; ** ; *** in relation to the day 0.