896341.fig.006a
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896341.fig.006b
(b)
896341.fig.006c
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896341.fig.006d
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896341.fig.006e
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896341.fig.006f
(f)
Figure 6: Histopathology. Photomicrograph of mice liver sections (staining with haematoxylin and eosin) ×40; (a) normal mice liver. (b) Iron-intoxicated (iron dextran, 100 mg/kg b.w.) liver section showing necrosis (N), fatty ballooning degeneration (FD), inflammation (I), and loss of cellular boundaries. (c) Liver section treated with iron dextran +50 mg/kg b.w. CCME showing improved histology with portal inflammation (PI). (d) Liver section treated with iron dextran +100 mg/kg b.w. CCME. (e) Liver section treated with iron dextran +200 mg/kg b.w. CCME. The two groups (d) and (e) show reduced hepatocellular necrosis, ballooning degeneration, and inflammation. (f) Liver section treated with iron dextran +20 mg/kg b.w. desirox also shows reduced necrotic area and increased number of hepatocytes.