Review Article

Prescription of Chinese Herbal Medicine and Selection of Acupoints in Pattern-Based Traditional Chinese Medicine Treatment for Insomnia: A Systematic Review

Table 3

The mean effective rate of pattern-based TCM treatments for insomnia.

TCM pattern
Chinese nameRandomized controlled trialsControlled trialsCase series
No. of studiesMean effective rate in %
(range, SD, 95% CI)
No. of studiesMean effective rate in %
(range, SD, 95% CI)
No. of studiesMean effective rate in %
(range, SD, 95% CI)

Chinese herbal medicine
Deficiency of both the heart and spleen 988.9
(68.8–100.0, 11.4, 80.2–97.7)
397.6
(92.9–100.0, 4.1, 87.4–107.9)
1786.5
(60.0–100.0, 12.1, 80.3–92.7)
Hyperactivity of fire due to yin deficiency 1086.1
(66.7–100.0, 9.8, 79.1–93.1)
379.2
(50.0–94.7, 25.3, 16.3–142.1)
1088.3
(66.7–100.0, 10.6, 80.7–95.9)
Liver-qi stagnation transforming into fire 695.0
(89.5–100.0, 4.7, 90.1–100.0)
296.7
(93.3–100.0, 4.7, 54.3–139.0)
879.1
(20.0–100.0, 28.6, 55.1–103.0)
Heart-kidney noninteraction 190.9
/
0/486.9
(84.9–89.7, 2.1, 83.5–90.3)
Internal disturbance of phlegm heat 584.4
(50.0–100.0, 20.7, 58.7–110.2)
1100.0
/
886.3
(43.3–100.0, 18.0, 71.2–101.3)
Qi deficiency of the heart and gallbladder 0/166.7
/
575.3
(26.7–100.0, 30.0, 38.1–112.5)
Liver fire flaming upward 0/0/180.0
/
Heart deficiency with timidity 579.4
(42.9–100.0, 22.0, 52.1–106.8)
187.5
/
177.8
/
Disharmony between spleen and stomach 0/0/188.9
/
Stomach disharmony 185.7
/
0/0/
Acupuncture
Deficiency of both the heart and spleen 494.4
(91.5–100.0, 3.9, 88.3–100.5)
383.4
(63.6–93.5, 17.1, 40.9–126.0)
1390.8
(69.2–100.0, 8.7, 85.5–96.0)
Hyperactivity of fire due to yin deficiency 481.9
(50.0–96.7, 21.8, 47.2–116.5)
487.7
(73.3–98.0, 10.4, 71.2–104.2)
988.8
(41.7–100.0, 18.3, 74.7–102.9)
Liver-qi stagnation transforming into fire 175.0
/
297.6
(96.6–98.3, 1.0, 88.3–106.9)
681.5
(50.0–100.0, 19.8, 60.7–102.2)
Heart-kidney noninteraction 190.9
/
195.0
/
596.3
(87.5–100.0, 5.6, 89.4–103.2)
Internal disturbance of phlegm heat 294.5
(88.9–100.0, 7.8, 23.9–165.0)
195.0
/
595.0
(90.0–100.0, 4.7, 89.2–100.9)
Qi deficiency of the heart and gallbladder 0/376.9
(75.0–80.8, 3.3, 68.6–85.2)
475.0
(0.0–100.0, 50.0, −4.6–154.6)
Liver fire flaming upward 292.9a  
/
0/387.9
(63.0–100.0, 21.0, 35.7–140.1)
Heart deficiency with timidity 1100.0
/
0/490.1
(70.0–100.0, 14.1, 67.6–112.6)
Disharmony between spleen and stomach 0/0/398.1
(94.4–100.0, 3.2, 90.1–106.2)
Stomach disharmony 2100.0a  
/
0/290.0
(80.0–100.0, 14.1, −37.1–217.1)

aEffective rate was the same in the 2 studies.