Meta-Analysis of Randomized Controlled Trials on the Efficacy of Di’ao Xinxuekang Capsule and Isosorbide Dinitrate in Treating Angina Pectoris
Table 3
Subgroups and sensitivity analysis based on ORs of ECG outcomes.
Group
No. of studies
No. of participants
OR
Wilcoxon test
95% CI
(effect)
(het)
M score
≤3
3
252
2.73
1.52, 4.91
3.35
0.0008
0%
0.24
0.89
>3
2
118
1.65
7
0.49, 5.57
0.8
0.42
49%
1.98
0.16
Sample size
<78
3
154
1.71
0.77, 3.84
1.31
0.19
0%
1.93
0.38
≥78
2
216
2.84
7
1.56, 5.20
3.39
0.0007
0%
0
0.99
No. of authors
1
3
276
2.91
1.65, 5.14
3.69
0.000 2
0%
0.05
0.97
>1
2
94
1.39
3
0.54, 3.55
0.68
0.5
4%
1.05
0.31
Publication year
<2005
2
166
1.75
0.54, 5.74
0.93
0.35
60%
2.47
0.12
≥2005
3
204
2.69
2
1.29, 5.60
2.63
0.008
0%
0.24
0.89
Trial date
Reported
2
118
1.65
0.49, 5.57
0.8
0.42
49%
1.98
0.16
Not reported
3
252
2.73
7
1.52, 4.91
3.35
0.0008
0%
0.24
0.89
Comparable
Reported
4
238
2.06
1.08, 3.93
2.19
0.03
0%
2.48
0.48
Not reported
1
132
2.83
1.37, 5.85
2.81
0.005
NA
NA
NA
AEs
Reported
3
250
2.22
1.14, 4.32
2.33
0.02
25%
2.66
0.26
Not reported
2
120
2.54
7
0.94, 6.90
1.83
0.07
0%
0.21
0.65
Improvement
>50%
5
370
2.37
1.46, 3.84
3.5
0.0005
0%
2.90
0.57
>80%
5
370
1.60
0
0.98, 2.60
1.88
0.06
0%
2.38
0.67
CI is confidence interval. NA is not available; Mann-Whitney-Wilcoxon test was performed on ORs of ECG. and (effect) evaluated the statistics of overall effect; , , and (het) were computed to assess heterogeneity.
