Synergistic Apoptosis-Inducing Antileukemic Effects of Arsenic Trioxide and <i>Mucuna macrocarpa</i> Stem Extract in Human Leukemic Cells via a Reactive Oxygen Species-Dependent Mechanism

<table>Expressions of apoptosis-related proteins in leukemia cells treated with arsenic trioxide (ATO), crude methanolic extract of <i>Mucuna macrocarpa</i> (CMEMM), and/or <i>N</i>-acetyl cysteine (NAC). Whole cell lysates were prepared from HL-60 or Jurkat cells treated with 2.5 <i>μ</i>M ATO, 50 <i>μ</i>g/mL CMEMM, 5 mM NAC, or indicated combinations for 24 h. Proteins as indicated were analyzed by Western blotting with <i>β</i>-actin as loading control. Representative blots shown were from one of three independent experiments.</table>

Evidence-Based Complementary and Alternative Medicine

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Figure 6: Synergistic Apoptosis-Inducing Antileukemic Effects of Arsenic Trioxide and <i>Mucuna macrocarpa</i> Stem Extract in Human Leukemic Cells via a Reactive Oxygen Species-Dependent Mechanism 

Figure 6 | Synergistic Apoptosis-Inducing Antileukemic Effects of Arsenic Trioxide and Mucuna macrocarpa Stem Extract in Human Leukemic Cells via a Reactive Oxygen Species-Dependent Mechanism 