Tanshinone IIA Inhibits Growth of Keratinocytes through Cell Cycle Arrest and Apoptosis: Underlying Treatment Mechanism of Psoriasis

<table>Clinical and pathological presentation of psoriasis and chemical structure of tanshinone IIA. (a) A 55-year-old woman with psoriasis suffered from erythematous plaques with limited silvery sale on her legs lasting as long as 5 years. (b) Epidermal regular psoriasiform hyperplasia in the epidermis and parakeratosis with Munro’s microabscesses. (c) Chemical structure of tanshinone IIA.</table>

Evidence-Based Complementary and Alternative Medicine

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Figure 1

Figure 1: Tanshinone IIA Inhibits Growth of Keratinocytes through Cell Cycle Arrest and Apoptosis: Underlying Treatment Mechanism of Psoriasis 