Tanshinone IIA Inhibits Growth of Keratinocytes through Cell Cycle Arrest and Apoptosis: Underlying Treatment Mechanism of Psoriasis

<table>DNA damage analysis by fragmentation assay and OxiSelect Comet assay. (a) DNA ladder was clearly observed at 10 <i>μ</i>g/mL concentration of tanshinone IIA. (b) OxiSelect Comet Assay Kit results of tanshinone IIA treatment. Keratinocytes were untreated (left) or treated (right) with tanshinone IIA (10 <i>μ</i>g/mL, 24 h) and analysis of apoptosis was performed by the Comet assay. (c) Graph represents means ± SD of percent of tail DNA% from 100 cells.</table>

Evidence-Based Complementary and Alternative Medicine

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Figure 6

Figure 6: Tanshinone IIA Inhibits Growth of Keratinocytes through Cell Cycle Arrest and Apoptosis: Underlying Treatment Mechanism of Psoriasis 