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Figure 5: Immunostaining of striatum with 4-HNE in a mice model of Parkinson's disease (PD) induced by MPTP. Staining was present within cell bodies. ###: as compared to the control group: **: as compared to MPTP group. (a) In control group, there was a few of 4-HNE immunoreactivity. (b) MPTP group: compared with control group, MPTP markedly increased the immunoreactivity of 4-HNE in mice striatum. (c) Low-dose group: no difference from MPTP group. (d) Middle-dose group: 4-HNE immunoreactivity are significantly reduced in striatum of brains in comparison to the MPTP group. (e) High-dose group: 4-HNE immunoreactivity are significantly reduced in striatum of brains in comparison to the MPTP group.