Suppressive Effect of Juzentaihoto on Vascularization Induced by B16 Melanoma Cells In Vitro and In Vivo

Figure 3

Effect of JTT on angiogenesis (MPCs). The ability of JTT to inhibit in vivo tumor-induced angiogenesis was examined by implantation of the MPCs containing B16 cells (1×10⁶ cells/animal) hypodermically intradermally on the shaven dorsum of animals. In the sham group, the vascularization occurred mildly. (a) The blood vessels images which were induced by B16-MPCs. (b) Neogenesis vascular length which was induced by B16-MPCs. *𝑃<0.05 (each group: 𝑛=10, mean ± SEM).

(a)

(b)