Research Article
Toxicity of a Novel Herbomineral Preparation Las01 on Human Cancer Cell Lines and Its Safety Profile in Humans and Animals
Table 1
Effect of acute administration of Las01 in rats.
| Parameters | Control | Las01 | Group 1 | Group 2 | Group 3 |
| Total WBCcount × 103 mm3
| 6293 ± 488
| 6342 ± 422
| 6321 ± 230
| 6234 ± 230
| Haemoglobin (gm%)
| 11.91 ± 1.85
| 11.82 ± 1.33
| 11.75 ± 1.0
| 11.82 ± 1.0
| Bilirubin total (mg/dL)
| 0.31 ± 0.13
| 0.30 ± 0.12
| 0.31 ± 0.15
| 0.32 ± 0.15
| Bilirubin direct (mg/dL)
| 0.24 ± 0.32
| 0.29 ± 0.27
| 0.25 ± 0.25
| 0.27 ± 0.15
| SGPT (U/L)
| 44.8 ± 11.5
| 45.7 ± 11.1
| 44.53 ± 12.38
| 46.11 ± 12.38
| SGOT (U/L) | 135.4 ± 19.6 | 139.3 ± 15.26 | 136.2 ± 17.25 | 133.4 ± 17.25 | ALP (U/L) | 161.8 ± 92.1 | 168.6 ± 93.2 | 170.7 ± 94.5 | 163.6 ± 91.5 | Albumin (mg/dL) | 3.53 ± 0.41 | 3.35 ± 0.46 | 3.71 ± 0.32 | 3.47 ± 0.32 | Globulin (mg/dL) | 4.03 ± 0.19 | 4.03 ± 0.36 | 4.00 ± 0.39 | 4.12 ± 0.39 | Total protein (gm%) | 7.56 ± 0.28 | 7.38 ± 0.22 | 7.71 ± 0.42 | 7.59 ± 0.42 | BUN (mg/dL) | 66.58 ± 7.45 | 63.13 ± 6.6 | 66.26 ± 7.48 | 65.32 ± 7.48 | Creatinine (mg/dL) | 0.45 ± 0.05 | 0.46 ± 0.04 | 0.44 ± 0.04 | 0.44 ± 0.04 | Sodium (mEq/L)
| 146 ± 4.41 | 147.5 ± 2.82 | 144.3 ± 5.6 | 148.3 ± 5.6 | Potassium (mEq/L)
| 4.15 ± 0.18 | 4.12 ± 0.39 | 4.14 ± 0. 23 | 4.16 ± 0. 23 | Chloride (mEq/L) | 104 ± 1.18 | 103 ± 1.68 | 101.8 ± 3.70 | 102.9 ± 3.70 |
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