Rhein Induces Apoptosis in Human Breast Cancer Cells

<table class="table-group" id="tab1"><tr><td><table class="table"><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr><td align="left" rowspan="2">Compounds</td><td align="center" rowspan="2">Structure</td><td align="center" colspan="2">IC50</td></tr><tr><td align="center">MCF-7/VE C</td><td align="center">MCF-7/HER2</td></tr><tr><td align="center" colspan="4"><hr/></td></tr><tr><td align="left">Rhein</td><td align="center"><img alt="1" src="https://static.hindawi.com/articles/ecam/volume-2012/952504/figures/1.jpg"/></td><td align="center">36.69 ±9.77 μg/mL (129.1 μM)</td><td align="center">30.66 ± 2.21 μg/mL (107.9 μM)</td></tr><tr><td align="left">Alo-emodin</td><td align="center"><img alt="2" src="https://static.hindawi.com/articles/ecam/volume-2012/952504/figures/2.jpg"/></td><td align="center">&gt;1000 μg/mL</td><td align="center">87.2 ± 12.0 μg/mL (322.7 μM)</td></tr><tr><td align="left">Emodin</td><td align="center"><img alt="3" src="https://static.hindawi.com/articles/ecam/volume-2012/952504/figures/3.jpg"/></td><td align="center">&gt;1000 μg/mL</td><td align="center">306.68 ± 6.57 μg/mL (1134.8 μM)</td></tr><tr><td align="left">Chrysophanol</td><td align="center"><img alt="4" src="https://static.hindawi.com/articles/ecam/volume-2012/952504/figures/4.jpg"/></td><td align="center">&gt;1000 μg/mL</td><td align="center">&gt;1000 μg/mL</td></tr><tr><td align="left">9,10-anthra quinone</td><td align="center"><img alt="5" src="https://static.hindawi.com/articles/ecam/volume-2012/952504/figures/5.jpg"/></td><td align="center">&gt;1000 μg/mL</td><td align="center">&gt;1000 μg/mL</td></tr><tr class="table-tr"><td colspan="4"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

 IC50 values of anthraquinone derivatives in MCF-7/VEC and MCF-7/HER2 cells.

Evidence-Based Complementary and Alternative Medicine

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Table 1

Table 1: Rhein Induces Apoptosis in Human Breast Cancer Cells 