Table 1: Features of the two series of experiments testing Gelsemium s. on mouse behaviour.

Series no. 1Series no. 2

Mouse producerHarlanCharles River
Housing4/cage2/cage
Light/dark cycleLight during day (h 7–19)Light during day (h 7–19)
Drug administration0.3 mL/day for 8 days, i.p.0.3 mL/day for 8 days, i.p.
Test sequence1st day: light-dark
2nd day: open field
1st day: open field
2nd day: light-dark
Test schedule30 min–320 min after last drug administration30 min–90 min after last injection
Number of complete experimentsControl (solvent)86
Diazepam51
Buspironen.t.5
Gels 4Cn.t.6
Gels 5C86
Gels 7C36
Gels 9Cn.t.6
Gels 30C26