Astragaloside IV Downregulates β-Catenin in Rat Keratinocytes to Counter LiCl-Induced Inhibition of Proliferation and Migration
Figure 5
LiCl induces S phase arrest in keratinocytes. (a) Keratinocytes were exposed to various concentrations of LiCl for 24 h. (b) Keratinocytes were exposed to 20 mM LiCl for 24 h, 48 h, and 72 h. (c) Histogram showing the average amounts of cells in various cell cycle stages from three experiments following a 24 h exposure to different LiCl concentrations. (d) Histogram showing the average distribution of cells in various cell cycle stages from three experiments with LiCl ± AS-IV, and LiCl + EGF treatments.
