Korean Red Ginseng Suppresses Metastasis of Human Hepatoma SK-Hep1 Cells by Inhibiting Matrix Metalloproteinase-2/-9 and Urokinase Plasminogen Activator

Figure 2

(a): Effects of WKRG and EKRG on MMP-2 and MMP-9 activities of SK-Hep1 cells. Cells were treated with various concentrations (0, 100, 200 and 400 μg/mL) of WKRG and EKRG for 24 h. The conditioned media were collected, and MMP-2 and MMP-9 activities were determined by gelatin zymography. (b) MMP-2 and MMP-9 activities were quantified by densitometric analyses. Values are expressed as means ± SD of three independent experiments. *𝑃<0.05, **𝑃<0.01, and ***𝑃<0.001 as compared with the untreated control.

(a)

(b)