Efficacy of Chuanxiong Ding Tong Herbal Formula Granule in the Treatment and Prophylactic of Migraine Patients: A Randomized, Double-Blind, Multicenter, Placebo-Controlled Trial
Table 2
Changes in VAS scores and pain intensity. (PPS, ).
Variable
Group
4 w
8 w
12 w
Follow-up period
CXDT-HFG group ()
4.96 ± 2.01
4.02 ± 2.33
2.39 ± 2.41
1.66 ± 2.15
VAS scores§
Placebo group ()
4.90 ± 2.09
4.12 ± 2.41
3.21 ± 2.45
2.92 ± 2.51
values
0.893
0.679
0.060
0.005‡
CXDT-HFG group ()
No pain, (%)
7 (8.14%)
15 (17.44%)
37 (43.02%)
49 (56.98%)
Mild, (%)
15 (17.44%)
24 (27.91%)
27 (31.40%)
23 (26.74%)
Moderate, (%)
57 (66.28%)
43 (50.00%)
21 (24.42%)
13 (15.12%)
Severe, (%)
7 (8.14%)
4 (4.65%)
1 (1.16%)
1 (1.16%)
Pain intensity#
Placebo group ()
No pain, (%)
4 (9.52%)
8 (19.05%)
12 (28.57%)
16 (38.10%)
Mild, (%)
9 (21.43%)
13 (30.95%)
11 (26.19%)
10 (23.81%)
Moderate, (%)
25 (59.52%)
19 (45.24%)
19 (45.24%)
16 (38.10%)
Severe, (%)
4 (9.52%)
2 (4.76%)
0 (0.00%)
0 (0.00%)
values
0.684
0.673
0.037‡
0.013‡
W: weeks. Significant difference, . Data presented as mean ± SD, number (percentage). for comparison with control group.
# values based on Chi-square test. § values based on repeated measures. ‡. Statistical differences for comparison between groups.
