Hepatoprotective Effects of Total Triterpenoids and Total Flavonoids from Vitis vinifera L against Immunological Liver Injury in Mice

Table 4

Influence of VTT and VTF on Th1/Th2 cytokine release in ILI mice.

Group	𝑛	Dose (mg/kg)	Th1		Th2
			IL-2 (pg/mL)	IFN-γ (pg/mL)	IL-4 (pg/mL)	IL-10 (pg/mL)
Normal	12		29.77±21.21	52.29±23.31	19.91±7.14	103.35±23.43
BCG + LPS	10		61.10±23.75^a	116.13±22.40^a	11.75±7.42^b	47.11±28.84^a
BCG + LPS + DDB	12	200	32.48±20.74^c	68.00±26.72^c	17.17±8.52	92.38±14.51^c
BCG + LPS + VTT	11	50	63.59±27.34	108.31±33.16	12.20±9.14	54.05±20.43
	11	150	54.87±20.85	94.01±32.32	14.78±8.87	67.77±21.59^d
	12	300	45.60±26.79	72.50±29.59^c	15.55±5.99	80.33±21.71^c
BCG + L PS + VTF	10	50	57.24±28.74	104.44±38.52	14.42±6.64	57.73±19.63
	12	150	43.95±22.40	90.95±29.24	15.47±6.71	81.94±19.04^c
	12	300	36.78±18.59^d	78.43±26.84^d	15.78±7.39	84.66±23.64^c

Values are the mean ± S.D. ^a𝑃<0.01, ^b𝑃<0.05, compared with normal group; ^c𝑃<0.01, ^d𝑃<0.01, compared with ILI model group.