Research Article

Rutin, a Flavonoid That Is a Main Component of Saussurea involucrata, Attenuates the Senescence Effect in D-Galactose Aging Mouse Model

Figure 4

Modulation of the cyclooxygenase-2 (COX-2) isozyme and NF-kappa B subunits (RELA and P50) by Saussurea involucrata (SI-2) or rutin pretreatment in D-galactose-treated (aged) mice. SI-2 or rutin pretreatment decreased this protein expression (a). SI-2 or rutin pretreatment also decreased COX-2 protein expression induced by D-galactose (b).
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(a)
980276.fig.004b
(b)