In Vivo and In Vitro Antinociceptive Effect of Fagopyrum cymosum (Trev.) Meisn Extracts: A Possible Action by Recovering Intestinal Barrier Dysfunction

Figure 4

Western blot of Fag treated rat colon TJs. (a) Protein of claudin-1, occludin, ZO-1, ZO-2. (b) Relative density analysis of concentration-dependent TJs of drug-treated groups and the controls. The values are expressed as mean ± SD (𝑛=3). ^a𝑃<0.05, ^aaa𝑃<0.001, compared with control rats; ^b𝑃<0.05, ^bb𝑃<0.01 compared with NMS+AA rats.

(a)

(b)