Phytochemical Characteristics, Free Radical Scavenging Activities, and Neuroprotection of Five Medicinal Plant Extracts

Table 3

Effects of the methanol extracts for five medicinal plants and positive control on PC12 cell viability.

Sample	Concentration (μg/mL)	Cell viability (%)
		12 hr	24 hr	48 hr	72 hr
Control	0	100.0 ± 11.9	100.0 ± 13.8	100 ± 14.8	100.0 ± 13.9
Spatholobus suberectus	0.25	102.0 ± 13.3	86.3 ± 12.8	102.0 ± 15.3	136.1 ± 15.8*
	0.5	174.4 ± 21.0***	122.9 ± 16.2	128.1 ± 12.0	208.0 ± 5.3***
	2.5	125.8 ± 12.2	106.8 ± 4.9	136.6 ± 4.2*	113.8 ± 11.9
	5.0	148.0 ± 8.9**	203.5 ± 22.3***	169.9 ± 17.3***	146.1 ± 15.3**
Uncaria rhynchophylla	0.25	99.6 ± 3.1	45.2 ± 5.0***	73.8 ± 4.2*	60.8 ± 1.8***
	0.5	110.6 ± 9.9	59.4 ± 4.5***	87.4 ± 2.1	73.3 ± 7.0*
	2.5	93.3 ± 15.6	69.4 ± 8.3**	72.4 ± 10.7*	57.4 ± 1.8***
	5.0	144.9 ± 6.4***	82.5 ± 10.3	64.7 ± 0.5***	57.6 ± 6.2***
Alpinia officinarum	0.25	77.6 ± 8.1	79.7 ± 9.3	78.9 ± 14.6	66.5 ± 1.5***
	0.5	102.3 ± 15.7	54.0 ± 3.0***	69.4 ± 2.7	77.0 ± 7.9
	2.5	50.0 ± 9.7***	69.3 ± 3.6*	101.1 ± 15.2	39.4 ± 3.7***
	5.0	89.3 ± 7.9	78.8 ± 11.3	82.0 ± 12.3	54.2 ± 6.7***
Drynaria fortunei	0.25	60.7 ± 8.7***	36.1 ± 1.9***	39.6 ± 5.3***	22.4 ± 0.8***
	0.5	60.0 ± 9.4***	37.5 ± 5.2***	44.2 ± 1.4***	35.1 ± 6.4***
	2.5	81.8 ± 7.7	35.4 ± 3.5***	49.4 ± 5.7***	36.9 ± 2.9***
	5.0	85.4 ± 6.4	35.7 ± 4.4***	49.0 ± 6.8***	25.4 ± 4.1***
Crataegus pinnatifida	0.25	60.7 ± 4.5**	79.7 ± 10.3	95.4 ± 5.7	44.3 ± 4.2***
	0.5	77.9 ± 4.1	53.9 ± 3.0***	117.1 ± 1.7	64.2 ± 8.0**
	2.5	105.9 ± 17.2	69.3 ± 3.6*	109.9 ± 9.1	27.1 ± 5.2***
	5.0	171.6 ± 9.3***	98.1 ± 8.1	111.1 ± 18.2	56.6 ± 9.4***
AC-DEVD-CHO	0.25	170.5 ± 23.8***	97.0 ± 16.7	95.5 ± 11.4	173.6 ± 27.7***
	0.5	76.9 ± 4.5	100.0 ± 12.0	99.1 ± 8.8	229.6 ± 17.0***
	2.5	222.0 ± 16.7***	120.2 ± 8.9	294.7 ± 26.6***	204.1 ± 15.5***
	5.0	189.3 ± 22.1***	129.0 ± 23.9	190.2 ± 22.3***	191.1 ± 19.1***

The data are presented as mean ± SD for three replicates.  *𝑃<0.05, **𝑃<0.01, ***𝑃<0.001 versus the control group without the addition of the sample solution.