Phytochemical Characteristics, Free Radical Scavenging Activities, and Neuroprotection of Five Medicinal Plant Extracts
Table 4
Protective effects of the methanol extracts for five medicinal plants and positive control on H2O2-induced PC12 cell death.
Sample
Concentration (μg/mL)
Cell viability (%)
Control
0
100.0 ± 7.3
H2O2
40 μM
59.0 ± 5.1#
Spatholobus suberectus
0.5
46.3 ± 3.1
2.5
67.4 ± 2.9
5.0
65.7 ± 7.9
Uncaria rhynchophylla
0.5
54.1 ± 1.6
2.5
61.0 ± 6.6
5.0
85.7 ± 5.6*
Alpinia officinarum
0.5
15.4 ± 3.0**
2.5
13.0 ± 1.2**
5.0
14.5 ± 2.8**
Drynaria fortunei
0.5
17.0 ± 1.5**
2.5
16.0 ± 0.9**
5.0
19.8 ± 1.5**
Crataegus pinnatifida
0.5
78.1 ± 10.0
2.5
83.4 ± 3.0*
5.0
107.2 ± 6.4**
AC-DEVD-CHO
0.5
23.9 ± 4.2**
2.5
19.7 ± 3.3**
5.0
37.5 ± 5.8
The data are presented as mean ± SD for three replicates. # versus the control group without the addition of the sample and H2O2 solutions. *; ** versus the 40 μM H2O2-treated group without the addition of the sample solution.
