Inhibition of Neurotoxic Secretory Phospholipases A2 Enzymatic, Edematogenic, and Myotoxic Activities by Harpalycin 2, an Isoflavone Isolated from Harpalyce brasiliana Benth

<table>Inhibition of myotoxic activity of sPLA2 (25 μg/mice) from Bothrops pirajai (PrTX-III), Crotalus durissus terrificus (Cdt F15), Apis mellifera (Apis) and Naja naja (Naja) venom expressed as creatine kinase release on plasma. (a) Native sPLA2 myotoxicity and (b) harpalycin 2 (Har2) treated sPLA2 myotoxicity. Data expressed as mean ± S.E.M. and analyzed by ANOVA followed by Dunnett’s test, with *P set at 0.05.</table>

Evidence-Based Complementary and Alternative Medicine

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Figure 4: Inhibition of Neurotoxic Secretory Phospholipases A2 Enzymatic, Edematogenic, and Myotoxic Activities by Harpalycin 2, an Isoflavone Isolated from Harpalyce brasiliana Benth

Figure 4 | Inhibition of Neurotoxic Secretory Phospholipases A2 Enzymatic, Edematogenic, and Myotoxic Activities by Harpalycin 2, an Isoflavone Isolated from Harpalyce brasiliana Benth 