Enhanced Antidepressant-Like Effects of Electroacupuncture Combined with Citalopram in a Rat Model of Depression

Figure 2

Rats show depressive-like symptoms after 4 weeks of CUS procedure. (a) Body weight. (b) Sucrose preference expressed as a ratio of the volume of sucrose solution consumption to the volume of total fluid intake. (c) The volume of consumption of sucrose solution, water, and total fluid. (d) FST. Data (expressed in seconds) are presented as time spent in immobility, climbing, and swimming. (e)–(g) OFT. Data (expressed in centimeter) are presented as movement distances in the floor plane (FP) (e) and vertical plane (VP) (f) and the number of entries into the arena-center (g). 𝑛=11–15 per group. Data represent mean ± SEM, ^∗𝑃<0.05, ^∗∗𝑃<0.01, and ^∗∗∗𝑃<0.001  versus the control group.

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