Baicalein Triggers Mitochondria-Mediated Apoptosis and Enhances the Antileukemic Effect of Vincristine in Childhood Acute Lymphoblastic Leukemia CCRF-CEM Cells

Figure 6

Involvement of the death receptor pathway in baicalein-induced apoptosis. Flow cytometric analysis of (a) Fas, (b) FasL, (c) DR4, and (d) DR5 expression levels following 24 h of various concentrations of baicalein exposure. The mean fluorescence intensities for each death receptor/ligand expression were tabulated. The data are represented as the mean ± SD in duplicate tests. The data are representative of three independent experiments showing similar results. *𝑃<0.05, compared with the untreated control group. **𝑃<0.01, compared with the untreated control group.

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