Baicalein Triggers Mitochondria-Mediated Apoptosis and Enhances the Antileukemic Effect of Vincristine in Childhood Acute Lymphoblastic Leukemia CCRF-CEM Cells

Figure 8

The effect of baicalein on the intracellular Ca²⁺ concentration. (a) CCRF-CEM cells were stained with Fluo-3 AM, followed by flow cytometry analysis 24 h post various concentrations of baicalein treatment. (b) The mean fluorescence intensities for the Ca²⁺ concentration were plotted. The data are represented as the mean ± SD in duplicate tests. Similar results were obtained in two independent experiments. *𝑃<0.05, compared with the 0.1% DMSO control group. **𝑃<0.01, compared with the 0.1% DMSO control group.

(a)  

(b)