Cardiovascular Protective Effects of Adjunctive Alternative Medicine (Salvia miltiorrhiza and Pueraria lobata) in High-Risk Hypertension

Table 1

Baseline characteristics of 90 hypertensive subjects.

Item	Placebo^1	D&G (1 gm)	D&G (2 gm)	D&G (1 gm + 2 gm)^2	𝑃 value	𝑃 value
	(𝑛=29)	(𝑛=31)	(𝑛=30)	(𝑛=61)		(1 versus 2)
Age	55.6±8.2	51.7±7.7	56.9±7.4	54.3±8.0	0.031	0.484
Gender
Male	20	27	20	47	0.134	0.445
Female	9	4	10	14
DM	18	11	17	28	0.091	0.152
LVH	12	13	10	23	0.749	0.738
CRF	10	12	12	24	0.901	0.657
Body weight (kg)	70.8±12.9	70.0±11.0	69.5±14.7	69.7±12.8	0.920	0.703
BMI (kg/m^2)	26.8±4.8	25.8±3.0	25.9±4.9	25.9±4.0	0.641	0.346
SBP (mmHg)	132.6±18.5	128.8±11.1	133.6±15.9	131.2±13.8	0.449	0.694
DBP (mmHg)	77.4±11.2	82.4±9.3	83.5±9.8	82.9±9.5	0.053	0.017
TC (mmol/L)	4.81±0.92	5.36±1.06	5.16±0.94	5.26±1.00	0.113	0.051
TG (mmol/L)	1.99±1.37	2.53±2.41	1.69±0.75	1.94±1.34	0.159	0.886
HBA1C (%)	7.46±2.62	6.81±2.04	6.41±0.99	6.60±1.57	0.251	0.180
Creatinine (umol/L)	110.0±40.6	127.9±57.9	110.1±49.3	119.1±54.2	0.278	0.421
FMD (%)	5.46±1.27	5.38±1.89	4.97±1.52	5.17±1.71	0.490	0.465
IMT (mm)	0.80±0.18	0.79±0.20	0.85±0.16	0.82±0.18	0.372	0.607

BMI: body mass index, CRF: chronic renal failure, DM: diabetis mellitus, DBP: diastolic blood pressure, FMD: flow-mediated dilation, HBA1-C: hemoglobin A1-C, IMT: intima-media thickness, LVH: left ventricular hypertrophy, SBP: systolic blood pressure, TC: total cholesterol, TG: triglyceride, 1: placebo, and 2: D&G (1 gm + 2 gm).