Electroacupuncture Reduces Cocaine-Induced Seizures and Mortality in Mice

Figure 3

Effects of EA at different frequencies (2 Hz, 50 Hz, and 100 Hz), needle insertion exerted at GV14 and GV20 acupoints, and sham EA (at bilateral SI11; 50 Hz) on cocaine-induced mortality rates. Mice were administered with cocaine (125 mg/kg; i.p.) at 1 min after EA or needle insertion and mortality was monitored for 1 hour. Between-group comparisons for each group were performed by chi-square test (*𝑃<0.05; **𝑃<0.01;***𝑃<0.001; n: the number of animals).