Replacements of Rare Herbs and Simplifications of Traditional Chinese Medicine Formulae Based on Attribute Similarities and Pathway Enrichment Analysis

Table 9

Pathways enriched by targets of FFDHT with 𝑃 values less than 0.01.

Number	Pathway name	𝑃 value
1	Pathways in cancer	4.96𝐸−16
2	Colorectal cancer	4.32𝐸−11
3	Prostate cancer	3.23𝐸−10
4	p53 signaling pathway	5.15𝐸−08
5	Pertussis	1.66𝐸−07
6	Small cell lung cancer	6.70𝐸−07
7	Influence of Ras and Rho proteins on G1 to S transition	1.44𝐸−06
8	Endometrial cancer	1.49𝐸−06
9	Pancreatic cancer	1.49𝐸−06
10	Amyotrophic lateral sclerosis (ALS)	1.78𝐸−06
11	Cytokines and inflammatory response	2.68𝐸−06
12	Bladder cancer	4.68𝐸−06
13	Tuberculosis	4.79𝐸−06
14	Amoebiasis	9.81𝐸−06
15	Apoptosis	1.27𝐸−05
16	HTLV-I infection	1.35𝐸−05
17	Cytokine network	1.45𝐸−05
18	RB tumor suppressor/checkpoint signaling in response to DNA damage	1.61𝐸−05
19	Apoptotic signaling in response to DNA damage	2.01𝐸−05
20	Chronic myeloid leukemia	3.19𝐸−05