Enhancement of Lymphangiogenesis In Vitro via the Regulations of HIF-1𝜶 Expression and Nuclear Translocation by Deoxyshikonin

Figure 2

Effects of deoxyshikonin on cord formation of HMVEC-dLy and HMVEC-d on Matrigel. (a), (c) Photographs of cord formation of HMVEC-dLy and HMVEC-d on Matrigel after incubation with or without 0.8 μM deoxyshikonin at 2 to 6 h (at ×400 magnification). (b), (d) The relative length of cords was measured using an Angiogenesis Image Analyzer. Data are the mean±SD (𝑛=3); ^∗𝑃<0.05, ^∗∗𝑃<0.01 compared with the control.

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