Table of Contents Author Guidelines Submit a Manuscript
Evidence-Based Complementary and Alternative Medicine
Volume 2013, Article ID 156489, 8 pages
http://dx.doi.org/10.1155/2013/156489
Research Article

Electroacupuncture Ameliorates Learning and Memory via Activation of the CREB Signaling Pathway in the Hippocampus to Attenuate Apoptosis after Cerebral Hypoperfusion

1Department of Rehabilitation Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
2Department of Rehabilitation Medicine, the Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510630, China

Received 29 April 2013; Revised 2 September 2013; Accepted 9 September 2013

Academic Editor: Ji-Sheng Han

Copyright © 2013 Xiaohua Han et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [14 citations]

The following is the list of published articles that have cited the current article.

  • Kaiyan Hui, Yang Yang, Kejian Shi, Hui Luo, Jing Duan, Jiajia An, Pa Wu, Yali Ci, Lei Shi, and Caimin Xu, “The p38 MAPK-regulated PKD1/CREB/Bcl-2 pathway contributes to selenite-induced colorectal cancer cell apoptosis in vitro and in vivo,” Cancer Letters, 2014. View at Publisher · View at Google Scholar
  • Bin Lu, Zhao Ma, Fei Cheng, Yan Zhao, Xin Zhang, Huijuan Mao, Xueyong Shen, and Sheng Liu, “Effects of electroacupuncture on ethanol-induced impairments of spatial learning and memory and Fos expression in the hippocampus in rats,” Neuroscience Letters, vol. 576, pp. 62–67, 2014. View at Publisher · View at Google Scholar
  • Mason Chin Pang Leung, Ka Keung Yip, Yuen Shan Ho, Flora Ka Wai Siu, Wai Chin Li, and Belinda Garner, “Mechanisms Underlying the Effect of Acupuncture on Cognitive Improvement: A Systematic Review of Animal Studies,” Journal of Neuroimmune Pharmacology, 2014. View at Publisher · View at Google Scholar
  • Jing Sun, Xiao-mei Shao, Fang Fang, Zui Shen, Yuan-yuan Wu, and Jian-qiao Fang, “Electroacupuncture alleviates retrieval of pain memory and its effect on phosphorylation of cAMP response element-binding protein in anterior cingulate cortex in rats,” Behavioral and Brain Functions, vol. 11, no. 1, 2015. View at Publisher · View at Google Scholar
  • Huayue Chen, Mitsuo Iinuma, Minoru Onozuka, and Kin-Ya Kubo, “Chewing maintains hippocampus-dependent cognitive function,” International Journal of Medical Sciences, vol. 12, no. 6, pp. 502–509, 2015. View at Publisher · View at Google Scholar
  • Qiu, Zeng, Zhou, Yang, Chen, and Guo, “Hypoxia-induced apoptosis and mitochondrial dysfunction in chondrocytes arising from CREB phosphorylation reduction,” Genetics and Molecular Research, vol. 15, no. 2, 2016. View at Publisher · View at Google Scholar
  • Chunyan Li, Hongwei Peng, and Xiaojie Li, “Effects of electroacupuncture on learning and memory ability and the expression of α7nAChR in rats with cerebral ischemia reperfusion injury,” Chinese Journal of Rehabilitation Medicine, vol. 31, no. 2, pp. 167–171, 2016. View at Publisher · View at Google Scholar
  • Mohammad Sharifzadeh, Maryam Kachooeian, Fariba Khodagholi, Soomaayeh Heysieattalab, Nasim Vosoughi, Mehdi Sanati, Leila Azimi, Asal Yans, Gelareh Vakilzadeh, and Ghorban Taghizadeh, “Protective effects of salicylate on PKA inhibitor (H-89)-induced spatial memory deficit via lessening autophagy and apoptosis in rats,” Pharmacology Biochemistry and Behavior, vol. 150-151, pp. 158–169, 2016. View at Publisher · View at Google Scholar
  • Cai-Xia Zheng, Feng Guo, Xiao-Lin Huang, Xiao-Hua Han, Min Lu, Ya-Bi Guo, Feng-Xia Zhang, and Hua Liu, “Electroacupuncture Ameliorates Learning and Memory and Improves Synaptic Plasticity via Activation of the PKA/CREB Signaling Pathway in Cerebral Hypoperfusion,” Evidence-based Complementary and Alternative Medicine, vol. 2016, 2016. View at Publisher · View at Google Scholar
  • Feng Guo, Jicheng Lou, Xiaohua Han, Yuguo Deng, and Xiaolin Huang, “Repetitive Transcranial Magnetic Stimulation Ameliorates Cognitive Impairment by Enhancing Neurogenesis and Suppressing Apoptosis in the Hippocampus in Rats with Ischemic Stroke,” Frontiers in Physiology, vol. 8, 2017. View at Publisher · View at Google Scholar
  • Jiao Liu, Chunyan Li, Kunqiang Yu, Jing Tao, Ruhui Lin, Lidian Chen, and Hongwei Peng, “Electroacupuncture attenuates learning and memory impairment via activation of α7nAChR-mediated anti-inflammatory activity in focal cerebral ischemia/reperfusion injured rats,” Experimental and Therapeutic Medicine, vol. 14, no. 2, pp. 939–946, 2017. View at Publisher · View at Google Scholar
  • Chulwon Kim, Jong Hyun Lee, Seung Ho Baek, Jeong-Hyeon Ko, Dongwoo Nam, and Kwang Seok Ahn, “Korean Red Ginseng Extract Enhances the Anticancer Effects of Sorafenib through Abrogation of CREB and c-Jun Activation in Renal Cell Carcinoma,” Phytotherapy Research, 2017. View at Publisher · View at Google Scholar
  • Kai Zhang, and Dianming Jiang, “RhoA inhibits the hypoxia-induced apoptosis and mitochondrial dysfunction in chondrocytes via positively regulating the CREB phosphorylation,” Bioscience Reports, vol. 37, no. 2, 2017. View at Publisher · View at Google Scholar
  • Wu, Li, Li, Zeng, and Wu, “Electroacupuncture ameliorates spatial learning and memory impairment via attenuating NOX2-related oxidative stress in a rat model of Alzheimer's disease induced by Aβ1-42,” Cellular and Molecular Biology, vol. 63, no. 4, pp. 38–45, 2017. View at Publisher · View at Google Scholar