Mechanism of Hepatoprotective Effect of Boesenbergia rotunda in Thioacetamide-Induced Liver Damage in Rats
Masson’s trichrome staining of representative livers sampled from rats in different experimental groups. (a) Normal liver did not show signs of collagen deposition in livers from a normal rat. (b) Severe collagen deposition (arrow) and severe fibrosis were seen in the livers from a cirrhosis rat. (c) Minor collagen deposition in the liver of a hepatoprotected rat treated with Silymarin. (d) Moderated collagen deposition and moderate congestion around the central vein in the liver of rats treated with low dose BR extract. (e) Mild collagen deposition was observed in the livers of rats treated with high dose BR extract (original magnification 20).