Table of Contents Author Guidelines Submit a Manuscript
Evidence-Based Complementary and Alternative Medicine
Volume 2013 (2013), Article ID 159237, 8 pages
http://dx.doi.org/10.1155/2013/159237
Research Article

Tongguan Capsule Protects against Myocardial Ischemia and Reperfusion Injury in Mice

1Intensive Care Laboratory, Guangdong Province Hospital of Chinese Medicine, 2nd Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510120, China
2Animal Laboratory, Guangdong Province Hospital of Chinese Medicine, 2nd Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510006, China
3Department of Oral and Maxillary Surgery, Stomatology Hospital of Guangzhou Medical University, Guangzhou 510140, China
4University of South Florida, Tampa, FL 33612, USA

Received 15 March 2013; Revised 19 July 2013; Accepted 1 August 2013

Academic Editor: Keji Chen

Copyright © 2013 Jianyong Qi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. R. Papp, M. Gönczi, M. Kovács, G. Seprényi, and A. Végh, “Gap junctional uncoupling plays a trigger role in the antiarrhythmic effect of ischaemic preconditioning,” Cardiovascular Research, vol. 74, no. 3, pp. 396–405, 2007. View at Google Scholar
  2. L. Nilsson, J. Hallén, D. Atar, L. Jonasson, and E. Swahn, “Early measurements of plasma matrix metalloproteinase-2 predict infarct size and ventricular dysfunction in ST-elevation myocardial infarction,” Heart, vol. 98, no. 1, pp. 31–36, 2012. View at Publisher · View at Google Scholar · View at Scopus
  3. N. Ueda, D. P. Zipes, and J. Wu, “Coronary occlusion and reperfusion promote early afterdepolarizations and ventricular tachycardia in a canine tissue model of type 3 long QT syndrome,” American Journal of Physiology, vol. 290, no. 2, pp. H607–H612, 2006. View at Publisher · View at Google Scholar · View at Scopus
  4. D. M. Yellon and D. J. Hausenloy, “Myocardial reperfusion injury,” New England Journal of Medicine, vol. 357, no. 11, pp. 1074–1135, 2007. View at Publisher · View at Google Scholar · View at Scopus
  5. A. S. Go, D. Mozaffarian, V. L. Roger et al., “Heart disease and stroke statistics—2013 update: a report from the American Heart Association,” Circulation, vol. 127, no. 1, pp. e6–e245, 2013. View at Publisher · View at Google Scholar
  6. A. T. Turer and J. A. Hill, “Pathogenesis of myocardial ischemia-reperfusion injury and rationale for therapy,” American Journal of Cardiology, vol. 106, no. 3, pp. 360–368, 2010. View at Publisher · View at Google Scholar · View at Scopus
  7. R. B. Jennings, H. M. Sommers, G. A. Smyth, H. A. Flack, and H. Linn, “Myocardial necrosis induced by temporary occlusion of a coronary artery in the dog,” Archives of Pathology, vol. 70, no. 7, pp. 68–78, 1960. View at Google Scholar
  8. Q. F. Chen, M. Z. Zhang, and C. Yang, “Experimental study of the myocardial protection on septic rats by tongguan capsule,” Chinese Journal of Integrated Traditional and Western Medicine, vol. 32, no. 9, pp. 1253–1258, 2012. View at Google Scholar
  9. B. J. Chen, J. X. Feng, X. X. Su et al., “Effects of tongguan capsule on post-myocardial infarction ventricular remodeling and cardiac function in rats,” Chinese Journal of Integrative Medicine, vol. 16, no. 2, pp. 157–161, 2010. View at Publisher · View at Google Scholar · View at Scopus
  10. Z. Yong, M. Z. Zhang, and L. Wang, “The influence of Tongguan Capsule effect on cardiac function and serum SDF-1 of post-intervention patients of coronary artery diseases,” Journal of New Chinese Medicine, vol. 43, no. 8, pp. 5–8, 2011. View at Google Scholar
  11. J. Li, M. Z. Zhang, B. J. Chen, and E. A. et al, “Effect of Tongguan capsule on post-intervention patients of coronary heart disease with qi-deficiency and blood stasis syndrome,” Chinese Journal of Integrated Traditional and Western Medicine, vol. 28, no. 1, pp. 32–35, 2008. View at Google Scholar · View at Scopus
  12. Z. Q. Qiao, M. Z. Zhang, H. Liu, K. L. Chen, and S. Li, “A randomized double-blinded placebo-controlled clinical study of Tongguan capsule improving cardiac functional parameter of patients after PCI,” Chinese Archives of Traditional Chinese Medicine, vol. 21, no. 7, pp. 882–883, 2003. View at Google Scholar
  13. J. Y. Qi, M. Z. Zhang, J. Li et al., “The influence of Tongguan Capsule on coronary re-stenosis and hemodynamic,” Journal of Traditional Chinese Medicine, vol. 21, no. 6, pp. 882–883, 2003. View at Google Scholar
  14. J. L. Chen, W. K. Wu, Y. L. Han et al., “The dose-response relationship of Tongguan Capsule reducing myocardial ischemia and the effect on nitric oxide,” Journal of Guangzhou University of Traditional Chinese Medicine, vol. 34, no. 4, pp. 301–306, 2007. View at Google Scholar
  15. C. Depre, L. Wang, X. Sui et al., “H11 kinase prevents myocardial infarction by preemptive preconditioning of the heart,” Circulation Research, vol. 98, no. 2, pp. 280–288, 2006. View at Publisher · View at Google Scholar · View at Scopus
  16. Y. Guo, D. N. Tukaye, W. J. Wu et al., “The COX-2/PGI2 receptor axis plays an obligatory role in mediating the cardioprotection conferred by the late phase of ischemic preconditioning,” PLoS One, vol. 7, no. 7, Article ID e41178, 2012. View at Publisher · View at Google Scholar
  17. Y. Guo, Q. Li, W. J. Wu et al., “Endothelial nitric oxide synthase is not necessary for the early phase of ischemic preconditioning in the mouse,” Journal of Molecular and Cellular Cardiology, vol. 44, no. 3, pp. 496–501, 2008. View at Publisher · View at Google Scholar · View at Scopus
  18. Q. Li, Y. Guo, Q. Ou et al., “Gene transfer as a strategy to achieve permanent cardioprotection II: rAAV-mediated gene therapy with heme oxygenase-1 limits infarct size 1 year later without adverse functional consequences,” Basic Research in Cardiology, vol. 106, no. 6, pp. 1367–1377, 2011. View at Publisher · View at Google Scholar · View at Scopus
  19. P. Ping, C. Song, J. Zhang et al., “Formation of protein kinase Cε-Lck signaling modules confers cardioprotection,” Journal of Clinical Investigation, vol. 109, no. 4, pp. 499–507, 2002. View at Publisher · View at Google Scholar · View at Scopus
  20. Y. T. Xuan, Y. Guo, Y. Zhu, O. L. Wang, G. Rokosh, and R. Bolli, “Endothelial nitric oxide synthase plays an obligatory role in the late phase of ischemic preconditioning by activating the protein kinase Cε-p44/42 mitogen-activated protein kinase-pSer-signal transducers and activators of transcription1/3 pathway,” Circulation, vol. 116, no. 5, pp. 535–544, 2007. View at Publisher · View at Google Scholar · View at Scopus
  21. J. Y. Qi, M. Xu, Z. Z. Lu, and Y. Y. Zhang, “14-3-3 inhibits insulin-like growth factor-I-induced proliferation of cardiac fibroblasts via a phosphatidylinositol 3-kinase-dependent pathway,” Clinical and Experimental Pharmacology and Physiology, vol. 37, no. 3, pp. 296–302, 2010. View at Publisher · View at Google Scholar · View at Scopus
  22. J. Qi, M. Xu, Z. Lu, and Y. Zhang, “Differential expression of 14-3-3ε during physiological, pathological cardiac hypertrophy and chronic heart failure in mice,” Gene Therapy and Molecular Biology, vol. 13, no. 1, pp. 71–81, 2009. View at Google Scholar · View at Scopus
  23. T. B. Garcia and G. T. Miller, Arrhythmia Recognition: The Art of Interpretation, Jones and Bartlett Publishers, Sudbury, Mass, USA, 2004.
  24. Y. Guo, W. J. Wu, Y. Qiu, X. L. Tang, Z. Yang, and R. Bolli, “Demonstration of an early and a late phase of ischemic preconditioning in mice,” American Journal of Physiology, vol. 275, no. 4, pp. H1375–H1387, 1998. View at Google Scholar · View at Scopus
  25. J. P. Monassier, “Reperfusion injury in acute myocardial infarction: from bench to cath lab. Part II: clinical issues and therapeutic options,” Archives of Cardiovascular Diseases, vol. 101, no. 9, pp. 565–575, 2008. View at Publisher · View at Google Scholar · View at Scopus
  26. X. H. Han, P. Liu, Y. Y. Zhang, N. Zhang, F. R. Chen, and J. F. Cai, “Astragaloside IV regulates expression of ATP-sensitive potassium channel subunits after ischemia-reperfusion in rat ventricular cardiomyocytes,” Journal of Traditional Chinese Medicine, vol. 31, no. 4, pp. 321–326, 2011. View at Google Scholar · View at Scopus
  27. Z. P. Li and Q. Cao, “Effects of astragaloside IV on myocardial calcium transport and cardiac function in ischemic rats,” Acta Pharmacologica Sinica, vol. 23, no. 10, pp. 898–904, 2002. View at Google Scholar · View at Scopus
  28. X. L. Xu, X. J. Chen, H. Ji et al., “Astragaloside IV improved intracellular calcium handling in hypoxia-reoxygenated cardiomyocytes via the sarcoplasmic reticulum Ca 2+-ATPase,” Pharmacology, vol. 81, no. 4, pp. 325–332, 2008. View at Publisher · View at Google Scholar · View at Scopus
  29. B. L. Zhao, W. Jiang, Y. Zhao, J. W. Hou, and W. J. Xin, “Scavenging effects of Salvia miltiorrhiza on free radicals and its protection for myocardial mitochondrial membranes from ischemia-reperfusion injury,” Biochemistry and Molecular Biology International, vol. 38, no. 6, pp. 1171–1182, 1996. View at Google Scholar · View at Scopus
  30. Y. Yin, Y. Guan, J. Duan et al., “Cardioprotective effect of Danshensu against myocardial ischemia/reperfusion injury and inhibits apoptosis of H9c2 cardiomyocytes via Akt and ERK1/2 phosphorylation,” European Journal of Pharmacology, vol. 699, no. 3, pp. 219–226, 2013. View at Google Scholar
  31. S. L. Hale and R. A. Kloner, “Myocardial temperature in acute myocardial infarction: protection with mild regional hypothermia,” American Journal of Physiology, vol. 273, no. 1, pp. H220–H227, 1997. View at Google Scholar · View at Scopus
  32. L. M. Schwartz, S. G. Verbinski, R. S. Vander Heide, and K. A. Reimer, “Epicardial temperature is a major predictor of myocardial infarct size in dogs,” Journal of Molecular and Cellular Cardiology, vol. 29, no. 6, pp. 1577–1583, 1997. View at Publisher · View at Google Scholar · View at Scopus
  33. L. H. Michael, M. L. Entman, C. J. Hartley et al., “Myocardial ischemia and reperfusion: a murine model,” American Journal of Physiology, vol. 269, no. 6, pp. H2147–H2154, 1995. View at Google Scholar · View at Scopus
  34. J. J. Hutter, R. Mestril, E. K. W. Tam, R. E. Sievers, W. H. Dillmann, and C. L. Wolfe, “Overexpression of heat shock protein 72 in transgenic mice decreases infarct size in vivo,” Circulation, vol. 94, no. 6, pp. 1408–1411, 1996. View at Google Scholar · View at Scopus