Research Article
Expression Profiling and Proteomic Analysis of JIN Chinese Herbal Formula in Lung Carcinoma H460 Xenografts
Table 5
Significantly enriched GO Biological process terms in the differentially expressed proteins between the JIN formula and the MOCK groups.
| GO category | Description | Total genes | Changed genes | Enrichment | |
| GO:0044237 | Cellular metabolic process | 4513 | 45 | 1.40 | −3.26 | GO:0044249 | Cellular biosynthetic process | 2322 | 26 | 1.58 | −2.22 | GO:0006139 | Nucleobase nucleoside nucleotide and nucleic acid metabolic process | 2350 | 26 | 1.56 | −2.14 | GO:0016032 | Viral reproduction | 343 | 16 | 6.56 | −8.93 | GO:0034621 | Cellular macromolecular complex subunit organization | 364 | 14 | 5.41 | −6.76 | GO:0006915 | Apoptosis | 784 | 13 | 2.33 | −2.53 | GO:0006414 | Translational elongation | 97 | 12 | 17.41 | −11.62 | GO:0006977 | DNA damage response signal transduction by p53 class mediator resulting in cell cycle arrest | 57 | 4 | 9.88 | −3.16 | GO:0072395 | Signal transduction involved in cell cycle check point | 57 | 4 | 9.88 | −3.16 |
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