Anti-Diabetic Activities of Jiaotaiwan in db/db Mice by Augmentation of AMPK Protein Activity and Upregulation of GLUT4 Expression

Figure 2

Effects of JTW on body weight, water intake, and food intake in db/db mice. (a) Body weight: body weight was measured every week after treatment (𝑛=8). (b) Water intake: mice were administered with JTW each day for two weeks (8.4 g kg⁻¹ day⁻¹), CC (7.6 g kg⁻¹ day⁻¹), CIN (0.76 g kg⁻¹ day⁻¹), or ROS (5 mg kg⁻¹ day⁻¹) in a vehicle using oral gavage. The water intake amount was recorded every 24 h throughout the treatment (𝑛=8). (c) Food intake: after treatment with gastric infusion for two weeks, water intake was recorded every 24 h throughout the treatment (𝑛=8). The data were shown as mean ± SE. *𝑃<0.05 compared with the model control group; **𝑃<0.01 compared with the model control group; ^##𝑃<0.01 compared with the JTW-treated group.

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