Anti-Diabetic Activities of Jiaotaiwan in db/db Mice by Augmentation of AMPK Protein Activity and Upregulation of GLUT4 Expression
Figure 3
Effects of JTW on fasting blood glucose, glucose tolerance, insulin tolerance, and fasting serum insulin level in db/db mice. (a) Fasting blood glucose levels after two-week treatment (). (b) Intraperitoneal glucose tolerance test (IPGTT) after two-week treatment. The mice were fasted for 12 h before measuring blood glucose levels at 0 min. A total of 1 g/kg body weight of glucose was intraperitoneally injected, and glucose levels were tested at regular intervals of 15, 30, 60, and 90 min (). (c), (d) Intraperitoneal insulin tolerance test (IPITT) was performed after three-week treatment. Glucose levels were tested in the same way after intraperitoneally injecting 1 μ/kg body weight of insulin (). Data are presented as mean ± SE. *, ** versus the model control group. #, ## versus JTW-treated group.
