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Evidence-Based Complementary and Alternative Medicine
Volume 2013 (2013), Article ID 183915, 9 pages
http://dx.doi.org/10.1155/2013/183915
Research Article

Influence of Propolis on Hygiene, Gingival Condition, and Oral Microflora in Patients with Cleft Lip and Palate Treated with Fixed Orthodontic Appliances

1Department of Orthodontics, Medical University of Silesia in Katowice, Plac Traugutta 2, 41-800 Zabrze, Poland
2Department of Oral Surgery, Medical University of Silesia in Katowice, Plac Akademicki 17, 41-902 Bytom, Poland
3Department of Microbiology and Immunology, Medical University of Silesia in Katowice, Jordana 19, 41-808 Zabrze, Poland
4Department of Conservative Dentistry with Endodontics, Medical University of Silesia in Katowice, Plac Akademicki 17, 41-902 Bytom, Poland

Received 29 March 2013; Accepted 27 April 2013

Academic Editor: Ewelina Szliszka

Copyright © 2013 Agnieszka Machorowska-Pieniążek et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The aim of this study was to evaluate the influence of 3% ethanol extract of propolis (EEP) on hygiene, gingival and microbiological status of oral cavity in patients with cleft lip and palate treated with fixed orthodontic appliances. The study included forty-one nonsyndromic complete unilateral of bilateral cleft lip and palate subjects with fixed appliance on at least 10 teeth. Twenty-one subjects were instructed to brush their teeth three times a day using toothpaste with propolis. Control group included twenty subjects who were asked to brush their teeth three times a day using a toothpaste without propolis. API, OPI, GI, and supragingival bacterial plaque were taken from each subject twice: baseline and after using the toothpaste for 35 days. The final examinations showed statistically significant decrease in OPI, GI, and the percentage of the Actinomyces spp. and Capnocytophaga spp. compared with baseline in propolis group subjects. The improvement in oral health in these patients confirms antibacterial, anti-inflammatory, and regenerative properties of propolis.